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癌症患者感染小囊腔菌:病例报告及文献复习。

Bloodstream Infection of a Cancer Patient by Cystobasidium minutum: A Case Report and Literature Review.

机构信息

Departamento de Medicina Tropical, Universidade Federal de Pernambuco, Recife, Brazil.

Departamento de Micologia, Universidade Federal de Pernambuco, Recife, Brazil.

出版信息

Mycopathologia. 2020 Apr;185(2):395-398. doi: 10.1007/s11046-019-00415-x. Epub 2020 Jan 2.

DOI:10.1007/s11046-019-00415-x
PMID:31897974
Abstract

Emergent fungal infections are uncommon conditions which frequently lead to death. To our knowledge, only a few cases of invasive infection by Cystobasidium minutum (previously known as Rhodotorula minuta) have been reported. Moreover, several factors are responsible for deep site infections, such as catheter-related fungemia. This report describes the first case report of Cystobasidium minutum causing fungemia in Brazil. The pathogens fungemia was demonstrated by catheter and blood culture-proven, and both yeasts were identified by sequences of D1/D2 rDNA region. After the end of antifungal therapy and catheter removal, a second blood culture was found to be negative and the clinical signs and symptoms of the patient improved.

摘要

真菌性急症感染较为少见,但常可导致死亡。据我们所知,仅有少数几例由小滑霉(先前被称为微小红酵母)引起的侵袭性感染的报告。此外,导管相关性真菌血症等多种因素可导致深部部位感染。本报告描述了巴西首例小滑霉导致真菌血症的病例报告。病原体通过导管和血液培养得到证实,通过 D1/D2 rDNA 区序列鉴定出两种酵母菌。在抗真菌治疗和导管移除结束后,第二次血培养结果为阴性,患者的临床症状和体征得到改善。

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本文引用的文献

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The Curious Case of "Case Report" of Infections Caused by Human and Animal Fungal Pathogens: An Educational Tool, an Online Archive, or a Format in Need of Retooling.人类和动物真菌病原体感染的“病例报告”之谜:教育工具、在线档案还是需要改进的格式。
Mycopathologia. 2018 Dec;183(6):879-891. doi: 10.1007/s11046-018-0314-1.
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Rhodotorula species infections in humans: A systematic review.人体罗地红酵母属感染:系统综述。
Mycoses. 2019 Feb;62(2):90-100. doi: 10.1111/myc.12856. Epub 2018 Oct 17.
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Two yeast species Cystobasidium psychroaquaticum f.a. sp. nov. and Cystobasidium rietchieii f.a. sp. nov. isolated from natural environments, and the transfer of Rhodotorula minuta clade members to the genus Cystobasidium.
拉丁美洲的稀有酵母:罕见却意义重大。
J Fungi (Basel). 2023 Jul 14;9(7):747. doi: 10.3390/jof9070747.
4
Begerowomyces aurantius sp. nov., a novel yeast isolated from koalas' habitat in a Japanese zoological park.金黄贝格尔酵母,一种从日本动物园考拉栖息地中分离出的新型酵母。
J Vet Med Sci. 2023 Mar 1;85(3):271-278. doi: 10.1292/jvms.22-0374. Epub 2023 Jan 18.
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Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes.养老院居民口腔护理教育后酵母菌种分布及口腔定植危险因素
J Fungi (Basel). 2022 Mar 17;8(3):310. doi: 10.3390/jof8030310.
从自然环境中分离出的两种酵母菌种,即新种嗜冷水生囊肿担子菌(Cystobasidium psychroaquaticum f.a. sp. nov.)和新种里氏囊肿担子菌(Cystobasidium rietchieii f.a. sp. nov.),以及将微小红酵母(Rhodotorula minuta)分支成员转移至囊肿担子菌属。
Antonie Van Leeuwenhoek. 2015 Jan;107(1):173-85. doi: 10.1007/s10482-014-0315-0. Epub 2014 Nov 1.
4
Rhodotorula minuta as onychomycosis agent in a Chinese patient: first report and literature review.微小毛孢子菌致甲真菌病 1 例并文献复习
Mycoses. 2014 Mar;57(3):191-5. doi: 10.1111/myc.12143. Epub 2013 Oct 11.
5
ESCMID and ECMM joint clinical guidelines for the diagnosis and management of rare invasive yeast infections.ESCMID 和 ECMM 联合临床指南:罕见侵袭性酵母真菌感染的诊断与管理。
Clin Microbiol Infect. 2014 Apr;20 Suppl 3:76-98. doi: 10.1111/1469-0691.12360.
6
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Identification and phylogeny of ascomycetous yeasts from analysis of nuclear large subunit (26S) ribosomal DNA partial sequences.通过分析核大亚基(26S)核糖体DNA部分序列对子囊菌酵母进行鉴定和系统发育分析。
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