Porikos K P, Koopmans H S
Department of Medical Physiology, University of Calgary, Alberta, Canada.
Appetite. 1988;11 Suppl 1:12-5.
Artificial sweeteners are used to provide a sweet taste to a food while removing the calories associated with sugar. The importance of non-nutritive sweeteners (NNS) for the control of body weight has never been proved. In this long-term study, 81 rats fed ad libitum on chow and water were given either an 11% sucrose solution, a solution artificially sweetened with saccharin and aspartame or served as controls. Over an 8-week period, the sucrose rats gained considerable weight while the NNS rats showed the same weight gain as controls. When the sweetened solutions were switched, obese sucrose rats lost weight during the next 8 weeks while rats previously on NNS gained weight rapidly. The results show that substitution of artificial sweeteners for sugars prevents weight gain and promotes weight loss in rats.
人工甜味剂用于为食物提供甜味，同时去除与糖相关的热量。非营养性甜味剂（NNS）对控制体重的重要性从未得到证实。在这项长期研究中，81只随意进食饲料和饮水的大鼠，分别给予11%的蔗糖溶液、用糖精和阿斯巴甜人工增甜的溶液或作为对照。在8周的时间里，蔗糖组大鼠体重显著增加，而非营养性甜味剂组大鼠的体重增加与对照组相同。当更换甜味溶液时，肥胖的蔗糖组大鼠在接下来的8周内体重减轻，而之前使用非营养性甜味剂的大鼠体重迅速增加。结果表明，用人工甜味剂替代糖可防止大鼠体重增加并促进体重减轻。
