Park In Woo, Kim Kyung Won, Hong Yunhwa, Yoon Hyun Ji, Lee Yonghun, Gwak Dham, Heo Kwang
Department of Nanotechnology and Advanced Materials Engineering, Sejong University, Seoul 05006, Korea.
Nanomaterials (Basel). 2020 Jan 2;10(1):93. doi: 10.3390/nano10010093.
Recently, biocompatible energy harvesting devices have received a great deal of attention for biomedical applications. Among various biomaterials, viruses are expected to be very promising biomaterials for the fabrication of functional devices due to their unique characteristics. While other natural biomaterials have limitations in mass-production, low piezoelectric properties, and surface modification, M13 bacteriophages (phages), which is one type of virus, are likely to overcome these issues with their mass-amplification, self-assembled structure, and genetic modification. Based on these advantages, many researchers have started to develop virus-based energy harvesting devices exhibiting superior properties to previous biomaterial-based devices. To enhance the power of these devices, researchers have tried to modify the surface properties of M13 phages, form biomimetic hierarchical structures, control the dipole alignments, and more. These methods for fabricating virus-based energy harvesting devices can form a powerful strategy to develop high-performance biocompatible energy devices for a wide range of practical applications in the future. In this review, we discuss all these issues in detail.
近年来，生物相容性能量收集装置在生物医学应用中受到了广泛关注。在各种生物材料中，病毒因其独特的特性有望成为制造功能器件非常有前景的生物材料。虽然其他天然生物材料在大规模生产、低压电性能和表面改性方面存在局限性，但作为一种病毒的M13噬菌体可能凭借其大规模扩增、自组装结构和基因改造克服这些问题。基于这些优势，许多研究人员已开始开发基于病毒的能量收集装置，这些装置表现出优于以往基于生物材料的装置的性能。为了提高这些装置的功率，研究人员尝试改变M13噬菌体的表面特性、形成仿生分级结构、控制偶极排列等。这些制造基于病毒的能量收集装置的方法可以形成一种强有力的策略，以开发高性能生物相容性能量装置，用于未来广泛的实际应用。在本综述中，我们将详细讨论所有这些问题。
