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生物压电性:基础及其在组织工程和再生医学中的应用

Bio-piezoelectricity: fundamentals and applications in tissue engineering and regenerative medicine.

作者信息

Kamel Nagwa Ahmed

机构信息

Microwave Physics and Dielectrics Department, Physics Research Institute, National Research Centre, Cairo, Egypt.

出版信息

Biophys Rev. 2022 Jun 28;14(3):717-733. doi: 10.1007/s12551-022-00969-z. eCollection 2022 Jun.

DOI:10.1007/s12551-022-00969-z
PMID:35783122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9243952/
Abstract

In recent years, smart materials have piqued the interest of scientists and physicians in the biomedical community owing to their ability to modify their properties in response to an external stimulation or changes in their surroundings. Biocompatible piezoelectric materials are an interesting group of smart materials due to their ability to produce electrical charges without an external power source. Electric signals produced by piezoelectric scaffolds can renew and regenerate tissues through special pathways like that found in the extracellular matrix. This review summarizes the piezoelectric phenomenon, piezoelectric effects generated within biological tissues, piezoelectric biomaterials, and their applications in tissue engineering and their use as biosensors.

摘要

近年来,智能材料因其能够响应外部刺激或周围环境变化而改变自身特性,引发了生物医学领域科学家和医生的兴趣。生物相容性压电材料是一类有趣的智能材料,因为它们能够在无需外部电源的情况下产生电荷。压电支架产生的电信号可以通过细胞外基质中发现的特殊途径来更新和再生组织。本文综述了压电现象、生物组织内产生的压电效应、压电生物材料及其在组织工程中的应用以及作为生物传感器的用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fa5/9250581/a3f0004c2e07/12551_2022_969_Fig7_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fa5/9250581/a3f0004c2e07/12551_2022_969_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fa5/9250581/7fa31a1335bc/12551_2022_969_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fa5/9250581/f093ff4d642a/12551_2022_969_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fa5/9250581/a3f0004c2e07/12551_2022_969_Fig7_HTML.jpg

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