Department of Epidemiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1 (9713 GZ), Groningen, The Netherlands.
National Autonomous University of Mexico (UNAM), Mexico City, Mexico.
J Cancer Surviv. 2020 Jun;14(3):377-385. doi: 10.1007/s11764-020-00854-2. Epub 2020 Jan 14.
To compare the differences in lifestyle behaviours between cancer survivors (CSs) and cancer-free participants in a large and representative population-based cohort.
We included 115,257 adults from the Lifelines cohort. Cancer status was self-reported, and health behaviours were measured (e.g. body mass index [BMI]) or assessed by questionnaire (e.g. physical activity, smoking, alcohol consumption, sedentary behaviour and diet). The data were then categorised for logistic regression analysis, stratified and adjusted by sex and age (< 55 vs ≥ 55 years).
CSs (5473; 4.7%) were diagnosed 9 ± 8.5 years before data collection, were older (mean age 55.4 vs 44.4 years) and more often female (66.6% vs 33.4%) than the cancer-free participants. They were also more likely to be physically active and to have a better diet, and also less likely to be alcohol drinkers; but, were more likely to have a higher BMI, be former smokers and to be sedentary. After adjustment for sex and age, however, BMI was more likely to be normal, physical activity was more likely to be higher and smoking to be prevalent in CSs. Current smoking was also significantly higher among females and those aged < 55 years who were CSs than for those with no history of cancer.
In this population-based cohort, CSs have health behaviour comparable to those without a cancer diagnosis.
Smoking cessation strategies should target all CSs, but efforts could yield greatest benefit if they target females and those younger than 55 years.
在一个大型代表性人群队列中，比较癌症幸存者（CSs）和无癌症参与者之间生活方式行为的差异。
我们纳入了 Lifelines 队列中的 115257 名成年人。癌症状况是自我报告的，健康行为通过测量（例如体重指数 [BMI]）或问卷调查（例如身体活动、吸烟、饮酒、久坐行为和饮食）进行评估。然后将数据分类进行逻辑回归分析，按性别和年龄（<55 岁与≥55 岁）分层和调整。
CSs（5473 人；4.7%）在数据收集前 9±8.5 年被诊断出患有癌症，他们比无癌症参与者年龄更大（平均年龄 55.4 岁比 44.4 岁）且更多为女性（66.6%比 33.4%）。他们也更可能积极参加身体活动和饮食更好，且不太可能饮酒；但他们更可能有较高的 BMI、更多的前吸烟者和久坐行为。然而，在调整性别和年龄后，CSs 的 BMI 更有可能正常，身体活动更有可能更高，吸烟更普遍。目前吸烟也在 CSs 中的女性和年龄<55 岁的人群中明显更高，高于无癌症史的人群。
在这个基于人群的队列中，CSs 的健康行为与无癌症诊断的人群相当。
戒烟策略应针对所有 CSs，但如果针对女性和年龄<55 岁的人群，努力可能会产生最大的效益。
