Stoleriu Stefania, Lungu Codruta, Ghitulica Cristina Daniela, Surdu Adrian, Voicu Georgeta, Cucuruz Andreia, Turculet Claudiu Stefan, Ciocan Lucian Toma
Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, RO-060041 Bucharest, Romania.
Department of Biomaterials and Medical Devices, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, RO-011061 Bucharest, Romania.
Nanomaterials (Basel). 2020 Jan 10;10(1):129. doi: 10.3390/nano10010129.
In this paper, ZnO and Co/Mg-doped ZnO thin films on TiAlV alloy substrates were obtained. The films were deposited by spin coating of sol-gel precursor solutions and thermally treated at 600 °C for 2 h, in air and slow cooled. The doping ions concentration was 1.0 mol%. The study's aim was to obtain implantable metallic materials with improved biocompatibility and antibacterial qualities. The characteristics of the thin films were assessed from the point of view of microstructure, morphology, wetting properties, antibacterial activity and biological response in the presence of amniotic fluid stem cells (AFSC). The results proved that all deposited samples were nanostructured, suggesting a very good antibacterial effect and proving to be suitable supports for cellular adhesion and proliferation. All properties also depended on the doping ion nature.
在本文中，在TiAlV合金基底上获得了ZnO以及Co/Mg掺杂的ZnO薄膜。通过旋涂溶胶 - 凝胶前驱体溶液来沉积薄膜，并在空气中于600°C热处理2小时，然后缓慢冷却。掺杂离子浓度为1.0 mol%。该研究的目的是获得具有改善的生物相容性和抗菌特性的可植入金属材料。从微观结构、形态、润湿性、抗菌活性以及在羊水干细胞（AFSC）存在下的生物学反应的角度评估了薄膜的特性。结果证明，所有沉积样品均为纳米结构，显示出非常好的抗菌效果，并证明是细胞粘附和增殖的合适载体。所有性能还取决于掺杂离子的性质。
