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日本对人乳头瘤病毒(HPV)疫苗接种态度的转变:对妇产科医生关于HPV疫苗当前看法的5年随访调查

Changing attitudes in Japan toward HPV vaccination: a 5-year follow-up survey of obstetricians and gynecologists regarding their current opinions about the HPV vaccine.

作者信息

Nagase Yoshikazu, Ueda Yutaka, Abe Hazuki, Yagi Asami, Sawada Masaaki, Nakagawa Satoshi, Hiramatsu Kosuke, Egawa-Takata Tomomi, Matsuzaki Shinya, Kobayashi Eiji, Kimura Toshihiro, Kimura Tadashi

机构信息

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine , Osaka, Japan.

Department of Obstetrics and Gynecology, Osaka Police Hospital , Osaka, Japan.

出版信息

Hum Vaccin Immunother. 2020 Aug 2;16(8):1808-1813. doi: 10.1080/21645515.2020.1712173. Epub 2020 Jan 16.

Abstract

In Japan, the governmental recommendation for HPV vaccination was suspended in June 2013 because of media reports of so-called adverse vaccine events. The HPV vaccination rate in Japan prior to this suspension was almost 70%, but fell afterward to almost zero. To explore ways to bolster HPV vaccination, between 2014 and 2019 we conducted three serial surveys of the opinions of obstetricians and gynecologists about HPV vaccination. This study aimed to discuss the changing attitudes found in this 5-year follow-up survey. In August 2014, January 2017, and June 2019, we posted questionnaires to about 570 obstetricians and gynecologists practicing in Osaka, Japan. All three surveys used the same structured and closed-ended questionnaire, including questions about their personal opinions regarding HPV vaccination. We compared our new results to those of the previous two surveys. The response rate for the latest survey was 51.1% (293/573), which was equivalent to the previous two surveys. Among the responders, 83.3% (244/293) now thought that the Japanese government should restart its HPV vaccine recommendation, and 84.6% (248/293) were already recommending HPV vaccines for teenagers in their daily care. Eleven of 30 doctors (36.7%) had their own teenage daughters vaccinated against HPV after the suspension of recommendation. The rate has maintained an increasing trend from the previous two surveys. This study indicated that the attitude of obstetricians and gynecologists in Japan toward HPV vaccination has changed positively over 5 years. The results should serve as an encouragement to resume the governmental recommendation of HPV vaccines.

摘要

在日本,由于媒体报道了所谓的疫苗不良事件,2013年6月政府暂停了人乳头瘤病毒(HPV)疫苗接种建议。在暂停之前,日本的HPV疫苗接种率几乎达到70%,但之后降至几乎为零。为了探索提高HPV疫苗接种率的方法,2014年至2019年期间,我们对妇产科医生关于HPV疫苗接种的意见进行了三次连续调查。本研究旨在讨论在这项为期5年的随访调查中发现的态度变化。2014年8月、2017年1月和2019年6月,我们向在日本大阪执业的约570名妇产科医生发放了问卷。所有三次调查都使用了相同的结构化封闭式问卷,包括关于他们对HPV疫苗接种个人意见的问题。我们将新结果与前两次调查的结果进行了比较。最新调查的回复率为51.1%(293/573),与前两次调查相当。在受访者中,83.3%(244/293)现在认为日本政府应该重新启动HPV疫苗接种建议,84.6%(248/293)已经在日常诊疗中为青少年推荐HPV疫苗。在建议暂停后,30名医生中有11名(36.7%)为自己十几岁的女儿接种了HPV疫苗。这一比例与前两次调查相比呈上升趋势。本研究表明,日本妇产科医生对HPV疫苗接种的态度在5年中发生了积极变化。这些结果应能鼓励政府恢复HPV疫苗接种建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f6/7482756/5bade1132116/KHVI_A_1712173_F0001_B.jpg

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