Renwick A G
Clinical Pharmacology Group, University of Southampton, UK.
Physiol Behav. 1994 Jan;55(1):139-43. doi: 10.1016/0031-9384(94)90021-3.
A review of published data shows that although intense sweeteners have been shown to increase hunger ratings in some studies in humans, this has not been a consistent and reproducible observation. Any slight effect on perceived hunger has not been translated into an increase in food ingestion or effects on blood concentrations of insulin or glucose. Studies on the covert substitution of caloric sweeteners by intense sweeteners have shown either a decrease or no change in body weight. The published database does not support the concept that the consumption of intense sweeteners results in a paradoxical increase in calorie intake and body weight.
对已发表数据的回顾表明，尽管在一些人体研究中，高强度甜味剂已被证明会提高饥饿评分，但这并非是一个一致且可重复的观察结果。对感知饥饿的任何轻微影响都未转化为食物摄入量的增加，也未对胰岛素或葡萄糖的血液浓度产生影响。关于用高强度甜味剂暗中替代热量甜味剂的研究表明，体重要么下降，要么没有变化。已发表的数据库并不支持高强度甜味剂的摄入会导致热量摄入和体重反常增加这一观点。
