Department of Agriculture, Crop Production and Rural Environment, University of Thessaly, N. Ionia, Magnissia, Greece.
Department of Plant Science, Pennsylvania State University, Pennsylvania, United States.
Curr Pharm Des. 2020;26(16):1816-1837. doi: 10.2174/1381612826666200203145851.
There is an increasing interest from the pharmaceutical and food industry in natural antioxidant and bioactive compounds derived from plants as substitutes for synthetic compounds. The genus Allium is one of the largest genera, with more than 900 species, including important cultivated and wild species, having beneficial health effects.
The present review aims to unravel the chemical composition of wild Allium species and their healthrelated effects, focusing on the main antioxidant compounds. For this purpose, a thorough study of the literature was carried out to compile reports related to health effects and the principal bioactive compounds. Considering the vast number of species, this review is divided into subsections where the most studied species are presented, namely Allium ampeloprasum, A. flavum, A. hookeri, A. jesdianum, A. neapolitanum, A. roseum, A. stipitatum, A. tricoccum, and A. ursinum, with an additional composite section for less studied species.
The information presented in this review was obtained from worldwide accepted databases such as Scopus, ScienceDirect, PubMed, Google Scholar and Researchgate, using as keywords the respective names of the studied species (both common and Latin names) and the additional terms of"antioxidants" "health effects" and "bioactive properties".
The genus Allium includes several wild species, many of which are commonly used in traditional and folklore medicine while others are lesser known or are of regional interest. These species can be used as sources of natural bioactive compounds with remarkable health benefits. Several studies have reported these effects and confirmed the mechanisms of action in several cases, although more research is needed in this field. Moreover, considering that most of the studies refer to the results obtained from species collected in the wild under uncontrolled conditions, further research is needed to elucidate the effects of growing conditions on bioactive compounds and to promote the exploitation of this invaluable genetic material.
制药和食品行业对源自植物的天然抗氧化剂和生物活性化合物越来越感兴趣，这些化合物可作为合成化合物的替代品。葱属是最大的属之一，有超过 900 个种，包括重要的栽培和野生种，具有有益的健康作用。
本综述旨在揭示野生葱属物种的化学成分及其与健康相关的作用，重点是主要的抗氧化化合物。为此，对文献进行了彻底研究，以汇编与健康作用和主要生物活性化合物相关的报告。考虑到物种数量众多，本综述分为几个小节，其中介绍了研究最多的物种，即 A. ampeloprasum、A. flavum、A. hookeri、A. jesdianum、A. neapolitanum、A. roseum、A. stipitatum、A. tricoccum 和 A. ursinum，此外还有一个较少研究的物种的综合部分。
本综述中呈现的信息来自全球公认的数据库，如 Scopus、ScienceDirect、PubMed、Google Scholar 和 Researchgate，使用研究物种的名称（通用名和学名）以及“抗氧化剂”“健康作用”和“生物活性特性”等附加术语作为关键词。
葱属包括几个野生种，其中许多种在传统和民间医学中常用，而其他种则鲜为人知或只在特定地区使用。这些物种可以作为天然生物活性化合物的来源，具有显著的健康益处。已有多项研究报告了这些作用，并在某些情况下证实了作用机制，但在该领域还需要进一步研究。此外，考虑到大多数研究都提到了从不受控制条件下野外采集的物种中获得的结果，需要进一步研究来阐明生长条件对生物活性化合物的影响，并促进对这种宝贵遗传材料的开发利用。
