Molecular Dermatology Research Center, Shiraz University of Medical Sciences, P.O. Box: 7134844119, Zand Avenue, Shiraz, Iran.
Research Center for Psychiatry and Behavioral Sciences, Department of Psychiatry, Shiraz University of Medical Sciences, Shiraz, Iran.
Health Qual Life Outcomes. 2020 Feb 3;18(1):20. doi: 10.1186/s12955-020-1278-7.
Vitiligo is caused by partial or complete destruction of melanocytes in the affected skin area and influences the patient's quality of life. Besides physical involvement, vitiligo patients experience a high level of stress. Depression and Anxiety are common psychiatric disorders in vitiligo patients.
This study, as the first study, evaluates hopelessness, anxiety, depression and general health of vitiligo patients in comparison with normal controls in an Iranian population.
Hundred patients with vitiligo and hundred healthy controls were examined. General health, depression, hopelessness and anxiety were evaluated based on general health questionnaire. Anxiety, depression and hopelessness levels were analyzed using Chi-Square, and the mean value of general health was evaluated through t-test.
The results showed that anxiety and hopelessness levels were significantly higher in vitiligo patients than those who are in healthy controls. This significant difference refers to high levels of anxiety and hopelessness among women with vitiligo. It was also found that the single patients were more anxious, hopeless and depressive, while the married patients were only more anxious and hopeless than those who are in the control group, respectively. General health of patients was significantly worse than in healthy controls. The low level of general health in patients was related to poorer level of general health among women with vitiligo.
It seems that women with vitiligo are more mentally stressed than men with vitiligo. Both singles and married vitiligo patients suffer from anxiety and hopelessness.
白癜风是由于受影响皮肤区域的黑素细胞部分或完全破坏引起的,会影响患者的生活质量。除了身体上的影响,白癜风患者还会承受很大的压力。抑郁和焦虑是白癜风患者常见的精神障碍。
本研究首次评估了伊朗人群中白癜风患者与正常对照者的绝望感、焦虑、抑郁和总体健康状况。
对 100 例白癜风患者和 100 例健康对照者进行了检查。采用一般健康问卷评估总体健康、抑郁、绝望和焦虑。采用卡方检验分析焦虑、抑郁和绝望水平,采用 t 检验评估总体健康的均值。
结果显示,与健康对照组相比,白癜风患者的焦虑和绝望水平显著更高。这种显著差异表明女性白癜风患者的焦虑和绝望程度较高。此外,还发现单身患者比已婚患者更焦虑、绝望和抑郁,而已婚患者仅比对照组更焦虑和绝望。患者的总体健康状况明显差于健康对照组。患者总体健康状况较差与女性白癜风患者的总体健康水平较差有关。
似乎女性白癜风患者比男性白癜风患者精神压力更大。单身和已婚的白癜风患者都患有焦虑和绝望。