Endris Toyba, Worede Abebaw, Asmelash Daniel
Department of Medical Laboratory Science, Dessie Referral Hospital, Dessie, Ethiopia.
Department of Clinical Chemistry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Diabetes Metab Syndr Obes. 2019 Dec 31;12:2799-2809. doi: 10.2147/DMSO.S225854. eCollection 2019.
Diabetes mellitus is becoming an epidemic public health problem in developing countries such as Ethiopia. As the International Diabetes Federation indicates, the number of adults living with diabetes globally has been increasing from time to time. If early screening and follow-up are done, diabetes is a manageable disease. However, diabetes study at the community level in Ethiopia is limited and scarce. Therefore, the present study was conducted to assess the current prevalence of DM, prediabetes and its associated factors in Dessie Town, Northeast Ethiopia.
A community-based cross-sectional study was conducted from January to March 2019 among people aged 18 years and above in Dessie Town, Northeast Ethiopia. A multistage sampling technique was used to select a total of 587 study participants. Sociodemographic and behavioral characteristic data were collected using a pretested semi-structured questionnaire. Venous blood samples were used to determine the level of blood glucose and lipid profile. Diagnosis and classification of diabetes mellitus and prediabetes were based on the criteria of the American Diabetes Association.
The prevalence of diabetes mellitus and prediabetes was 6.8% (95% CI 4.9-9.0) and 15.7% (95% CI 12.9-18.7), respectively. The prevalence of previously undiagnosed diabetes mellitus was 72.5%. Positive family history of diabetes mellitus (AOR: 20.24, 95% CI 4.74-86.43), smoking habit (AOR: 12.12, 95% CI 2.30-63.73), overweight (AOR: 21.95, 95% CI 6.73-71.603), systolic hypertension (AOR: 4.61, 95% CI 1.09-19.50) and hypercholesterolemia (AOR: 8.97, 95% CI 2.05-39.23) were significantly associated with diabetes mellitus. Prediabetes was associated with advanced age (AOR: 3.55, 95% CI 1.16-10.79), marital status (single) (AOR: 3.06, 95% CI 1.40-6.67), educational status (illiterate) (AOR: 2.35, 95% CI 1.04-5.35) and overweight (AOR: 2.11, 95% CI 1.05-4.23).
There was a higher prevalence of diabetes mellitus and prediabetes. In addition, the prevalence of undiagnosed diabetes mellitus was high in our study area. Therefore, targeting the control and prevention strategy to such modifiable risk factors associated with diabetes and prediabetes may contribute to the reduction of the prevalence and further complications of diabetes mellitus.
糖尿病在埃塞俄比亚等发展中国家正成为一个流行的公共卫生问题。正如国际糖尿病联盟所指出的,全球成年糖尿病患者数量一直在不断增加。如果能进行早期筛查和随访,糖尿病是一种可控制的疾病。然而,埃塞俄比亚社区层面的糖尿病研究有限且匮乏。因此,本研究旨在评估埃塞俄比亚东北部德西镇糖尿病、糖尿病前期的当前患病率及其相关因素。
2019年1月至3月在埃塞俄比亚东北部德西镇对18岁及以上人群开展了一项基于社区的横断面研究。采用多阶段抽样技术共选取587名研究参与者。使用经过预测试的半结构化问卷收集社会人口学和行为特征数据。采集静脉血样以测定血糖和血脂水平。糖尿病和糖尿病前期的诊断与分类依据美国糖尿病协会的标准。
糖尿病和糖尿病前期的患病率分别为6.8%(95%置信区间4.9 - 9.0)和15.7%(95%置信区间12.9 - 18.7)。既往未诊断出的糖尿病患病率为72.5%。糖尿病家族史阳性(比值比:20.24,95%置信区间4.74 - 86.43)、吸烟习惯(比值比:12.12,95%置信区间2.30 - 63.73)、超重(比值比:21.95,95%置信区间6.73 - 71.603)、收缩期高血压(比值比:4.61,95%置信区间1.09 - 19.50)和高胆固醇血症(比值比:8.97,95%置信区间2.05 - 39.23)与糖尿病显著相关。糖尿病前期与高龄(比值比:3.55,95%置信区间1.16 - 10.79)、婚姻状况(单身)(比值比:3.06,95%置信区间1.40 - 6.67)、教育程度(文盲)(比值比:2.35,95%置信区间1.04 - 5.35)和超重(比值比:2.11,95%置信区间1.05 - 4.23)相关。
糖尿病和糖尿病前期的患病率较高。此外,在我们的研究区域,未诊断出的糖尿病患病率较高。因此,针对与糖尿病和糖尿病前期相关的这些可改变的危险因素制定控制和预防策略,可能有助于降低糖尿病的患病率及进一步的并发症。