Idowu Bukunmi Michael, Onigbinde Stephen Olaoluwa, Ebie Isaiah Uzezi, Adeyemi Michael Temidayo
Department of Radiology, Union Diagnostics and Clinical Services Plc, Yaba, Lagos, Nigeria.
Department of Radiology, Obafemi Awolowo University Teaching Hospitals Complex, Ile - Ife, Osun state, Nigeria.
J Ultrason. 2019 Dec;19(79):269-275. doi: 10.15557/JoU.2019.0040. Epub 2019 Dec 31.
This study aimed to evaluate the prevalence of gallbladder disease in gravid Nigerian women and to elucidate any association with gravidity and ABO blood group.
This was a descriptive cross-sectional study of six hundred and fifty-six (656) pregnant women recruited from March 2015 to March 2016. Hemoglobin genotype and blood group were recorded and a sonographic examination was performed using Siemens ultrasound scanner. Statistical analysis was done using STATA software for Windows.
Age had a significant association with the occurrence of gallbladder diseases (Likelihood ratio = 7.116, = 0.03). Two (0.3%) pregnant women had biliary sludge, 11 (1.7%) had gallstones while 643 (98%) had normal gallbladders. Also, only one (9.1%) primigravida woman with gallstone was found in this study while 10 (90.9%) of the women with gallstones were multigravida. All the pregnant women who had gallstone(s) had blood group O. Of the two women with biliary sludge; one had blood group A while the other had blood group O.
The incidence of gallbladder disease increased with age in this study. There was a higher prevalence of gallstones than sludge in pregnancy. Also, the incidence of gallstones increased with the number of pregnancies among the women with gallstones. Attention should be paid to the gallbladder during abdominal sonography in pregnancy.
本研究旨在评估尼日利亚孕妇胆囊疾病的患病率，并阐明其与妊娠次数及ABO血型之间的关联。
这是一项描述性横断面研究，研究对象为2015年3月至2016年3月招募的656名孕妇。记录血红蛋白基因型和血型，并使用西门子超声扫描仪进行超声检查。使用Windows版STATA软件进行统计分析。
年龄与胆囊疾病的发生存在显著关联（似然比=7.116，P=0.03）。两名（0.3%）孕妇有胆泥，11名（1.7%）有胆结石，而643名（98%）孕妇胆囊正常。此外，本研究中仅发现一名（9.1%）患有胆结石的初产妇，而10名（90.9%）患有胆结石的孕妇为经产妇。所有患有胆结石的孕妇血型均为O型。在两名有胆泥的孕妇中，一名血型为A型，另一名血型为O型。
在本研究中，胆囊疾病的发病率随年龄增长而增加。孕期胆结石的患病率高于胆泥。此外，患有胆结石的孕妇中，胆结石的发病率随妊娠次数增加而升高。孕期腹部超声检查时应关注胆囊情况。
