He Ming, Chen Man, Dou Yao, Ding Jiao, Yue Hangbo, Yin Guoqiang, Chen Xunjun, Cui Yingde
College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Innovation and Practice Base for Postdoctors, Chengdu Polytechnic, Chengdu 610041, China.
Polymers (Basel). 2020 Feb 3;12(2):305. doi: 10.3390/polym12020305.
Feathers, which contain >90% keratin, are valuable natural protein resources. The aim of this study is to prepare antimicrobial feather keratin (FK)-based nanofibers by incorporating silver nanoparticles (AgNPs). A series of AgNPs-embedded feather keratin/poly(vinyl alcohol)/poly(ethylene oxide) (FK/PVA/PEO) composite nanofibers with varying amounts of AgNPs content were fabricated by electrospinning. Their morphology, crystallinity, thermal stability, tensile property, and antibacterial activity were systematically investigated. The average diameters of composite nanofibers gradually decreased with increases in the amount of AgNPs. The crystallinity, thermal stability, and antibacterial activity of FK/PVA/PEO nanofibers were enhanced by embedding AgNPs. When embedded with 1.2% AgNPs, both the tensile strength and elongation-at-break reached the highest level. This work has the potential to expand the application of FK-based nanofibers in the biomaterial field.
羽毛含有超过90%的角蛋白，是宝贵的天然蛋白质资源。本研究的目的是通过掺入银纳米颗粒（AgNPs）来制备基于抗菌羽毛角蛋白（FK）的纳米纤维。通过静电纺丝制备了一系列含有不同含量AgNPs的AgNPs嵌入羽毛角蛋白/聚乙烯醇/聚环氧乙烷（FK/PVA/PEO）复合纳米纤维。系统研究了它们的形态、结晶度、热稳定性、拉伸性能和抗菌活性。复合纳米纤维的平均直径随着AgNPs含量的增加而逐渐减小。通过嵌入AgNPs提高了FK/PVA/PEO纳米纤维的结晶度、热稳定性和抗菌活性。当嵌入1.2%的AgNPs时，拉伸强度和断裂伸长率均达到最高水平。这项工作有可能扩大基于FK的纳米纤维在生物材料领域的应用。
