Gartside P S
University of Cincinnati Medical Center, OH 45267.
Environ Health Perspect. 1988 Jun;78:31-4. doi: 10.1289/ehp.887831.
In performing research for associations and relationships among the data thus far published from the NHANES II survey, only the data for the 64 communities involved may be used. The simple omission of a few essential data makes impossible any valid analysis from the data for the 20,325 individual respondents. In this research for associations between blood lead levels and blood pressure in NHANES II, the method of forward stepwise regression was used. This avoids the problem of inflated error rates for blood lead, maximizes the number of data analyzed, and minimizes the number of independent variables entered into the regression model, thus avoiding the pitfalls that previous NHANES II research of blood lead and blood pressure has fallen into when using backward stepwise regression. The results of this research for white male adults, white female adults, and black adults were contradictory and lacked consistency and reliability. In addition, the overall average association between blood lead level and blood pressure was so minute that the only rational conclusion is that there is no evidence for this association to be found in the NHANES II data.
在对美国国家健康与营养检查调查第二轮（NHANES II）迄今已发表的数据之间的关联和关系进行研究时，仅可使用涉及的64个社区的数据。仅仅遗漏一些关键数据，就使得对20325名个体受访者的数据进行任何有效分析都变得不可能。在这项关于NHANES II中血铅水平与血压之间关联的研究中，使用了向前逐步回归方法。这避免了血铅错误率膨胀的问题，最大化了分析的数据数量，并最小化了纳入回归模型的自变量数量，从而避免了NHANES II之前关于血铅与血压的研究在使用向后逐步回归时所陷入的陷阱。这项针对成年白人男性、成年白人女性和成年黑人的研究结果相互矛盾，缺乏一致性和可靠性。此外，血铅水平与血压之间的总体平均关联非常微小，以至于唯一合理的结论是，在NHANES II数据中找不到这种关联的证据。
