Group of Clinical and Experimental Allergy, Clinic "IPS Universitaria", University of Antioquia, Medellín, Colombia.
Medicine Department, University Corporation, Rafael Nuñez, Cartagena, Colombia.
Pulm Med. 2020 Jan 24;2020:6365314. doi: 10.1155/2020/6365314. eCollection 2020.
IgE sensitization (atopy) to pets is commonly evaluated using pet dander extracts. However, the diagnosis by components seems to be more adequate to evaluate the clinical relevance (allergy) of sIgE sensitization.
To study the association between IgE sensitization to pet allergen components and clinical symptoms. . Dander extracts and sIgE levels to pet components (Can f 1, Can f 2, Can f 3, Can f 5, Fel d 1, Fel 2, and Fel 4) were measured in a rhinitis group ( = 101) and a control group ( = 101) and a control group (.
Dog (34.6% vs. 23.5%) and cat dander (26.7% vs. 8.8%, = 0.05) IgE sensitization was frequent among rhinitis and no-rhinitis subjects, and it was similar to dog (29.7% vs. 20.5%) and cat (18.8% vs. 8.8%) components. Polysensitization for dog (3.1, 95% CI: 1.5 to 6.1, = 0.05) IgE sensitization was frequent among rhinitis and no-rhinitis subjects, and it was similar to dog (29.7% vs. 20.5%) and cat (18.8% vs. 8.8%) components. Polysensitization for dog (3.1, 95% CI: 1.5 to 6.1, = 0.05) IgE sensitization was frequent among rhinitis and no-rhinitis subjects, and it was similar to dog (29.7% vs. 20.5%) and cat (18.8% vs. 8.8%) components. Polysensitization for dog (3.1, 95% CI: 1.5 to 6.1.
Sensitization to pet dander extract identifies atopic patients, but its utility to predict clinical relevance is poor. Allergenic components could help to define the clinical relevance of sensitization to furry animals and could reduce the need for provocation test.
使用宠物皮屑提取物通常可以评估 IgE 致敏（过敏）。然而，成分诊断似乎更适合评估 sIgE 致敏的临床相关性（过敏）。
研究宠物过敏原成分的 IgE 致敏与临床症状之间的关系。在鼻炎组（n=101）和对照组（n=101）中测量皮屑提取物和 sIgE 对宠物成分（Can f 1、Can f 2、Can f 3、Can f 5、Fel d 1、Fel 2 和 Fel 4）的致敏水平。
鼻炎和非鼻炎患者中，狗（34.6%比 23.5%）和猫皮屑（26.7%比 8.8%，P=0.05）的 IgE 致敏率较高，与狗（29.7%比 20.5%）和猫（18.8%比 8.8%）的成分相似。鼻炎和非鼻炎患者中，狗（3.1，95%CI：1.5 至 6.1，P=0.05）的 IgE 致敏呈多态性，与狗（29.7%比 20.5%）和猫（18.8%比 8.8%）的成分相似。鼻炎和非鼻炎患者中，狗（3.1，95%CI：1.5 至 6.1，P=0.05）的 IgE 致敏呈多态性，与狗（29.7%比 20.5%）和猫（18.8%比 8.8%）的成分相似。鼻炎和非鼻炎患者中，狗（3.1，95%CI：1.5 至 6.1，P=0.05）的 IgE 致敏呈多态性，与狗（29.7%比 20.5%）和猫（18.8%比 8.8%）的成分相似。鼻炎和非鼻炎患者中，狗（3.1，95%CI：1.5 至 6.1，P=0.05）的 IgE 致敏呈多态性，与狗（29.7%比 20.5%）和猫（18.8%比 8.8%）的成分相似。鼻炎和非鼻炎患者中，狗（3.1，95%CI：1.5 至 6.1，P=0.05）的 IgE 致敏呈多态性，与狗（29.7%比 20.5%）和猫（18.8%比 8.8%）的成分相似。
对宠物皮屑提取物的致敏可识别出过敏患者，但预测临床相关性的效果不佳。过敏原成分有助于确定对毛茸茸动物致敏的临床相关性，并减少对激发试验的需求。
