Chan Sanny K, Leung Donald Y M
Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO. USA.
Division of Pediatric Allergy-Immunology, National Jewish Health, Denver, CO, USA.
Allergy Asthma Immunol Res. 2018 Mar;10(2):97-105. doi: 10.4168/aair.2018.10.2.97.
Allergies to dogs and cats affect 10%-20% of the population worldwide and is a growing public health concern as these rates increase. Given the prevalence of detectable dog and cat allergens even in households without pets, there is a critical need to accurately diagnose and treat patients to reduce morbidity and mortality from exposure. The ability to diagnose cat sensitization is good, in contrast to dogs. Component resolved diagnostics of sensitization to individual allergenic proteins will dramatically improve diagnosis. This review focuses on the current state of knowledge regarding allergies to dogs and cats, recent advances, therapies such as subcutaneous immunotherapy, and discusses important areas to improve diagnosis and therapy.
对狗和猫的过敏影响着全球10%-20%的人口，并且随着这些比例的上升，这一问题日益成为公共卫生关注的焦点。鉴于即使在没有宠物的家庭中也存在可检测到的狗和猫过敏原，准确诊断和治疗患者以降低因接触过敏原而导致的发病率和死亡率至关重要。与狗相比，诊断猫致敏的能力较好。针对个体变应原蛋白致敏的组分分辨诊断将显著改善诊断。本综述重点关注狗和猫过敏的当前知识状态、最新进展、皮下免疫疗法等治疗方法，并讨论改善诊断和治疗的重要领域。
