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Recent Advancements of Magnetic Nanomaterials in Cancer Therapy.

作者信息

Mukherjee Sudip, Liang Lily, Veiseh Omid

机构信息

Department of Bioengineering, George R. Brown School of Engineering, Rice University, Houston, TX 77005, USA.

出版信息

Pharmaceutics. 2020 Feb 11;12(2):147. doi: 10.3390/pharmaceutics12020147.

DOI:10.3390/pharmaceutics12020147
PMID:32053995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7076668/
Abstract

Magnetic nanomaterials belong to a class of highly-functionalizable tools for cancer therapy owing to their intrinsic magnetic properties and multifunctional design that provides a multimodal theranostics platform for cancer diagnosis, monitoring, and therapy. In this review article, we have provided an overview of the various applications of magnetic nanomaterials and recent advances in the development of these nanomaterials as cancer therapeutics. Moreover, the cancer targeting, potential toxicity, and degradability of these nanomaterials has been briefly addressed. Finally, the challenges for clinical translation and the future scope of magnetic nanoparticles in cancer therapy are discussed.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/9b5be8d2a945/pharmaceutics-12-00147-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/189b8d085592/pharmaceutics-12-00147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/161b16db1f32/pharmaceutics-12-00147-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/67bfc15d65d8/pharmaceutics-12-00147-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/3438271f3b23/pharmaceutics-12-00147-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/9b5be8d2a945/pharmaceutics-12-00147-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/189b8d085592/pharmaceutics-12-00147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/161b16db1f32/pharmaceutics-12-00147-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/67bfc15d65d8/pharmaceutics-12-00147-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/3438271f3b23/pharmaceutics-12-00147-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3279/7076668/9b5be8d2a945/pharmaceutics-12-00147-g005.jpg

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本文引用的文献

[1]
Improved delivery of doxorubicin using rationally designed PEGylated platinum nanoparticles for the treatment of melanoma.

Mater Sci Eng C Mater Biol Appl. 2019-11-5

[2]
Recent Advances of Plasmonic Gold Nanoparticles in Optical Sensing and Therapy.

Curr Pharm Des. 2019

[3]
MXD3 antisense oligonucleotide with superparamagnetic iron oxide nanoparticles: A new targeted approach for neuroblastoma.

Nanomedicine. 2019-11-26

[4]
Strategies based on metal-based nanoparticles for hypoxic-tumor radiotherapy.

Chem Sci. 2019-6-11

[5]
Discriminating nanoparticle core size using multi-contrast MPI.

Phys Med Biol. 2019-3-29

[6]
Stealth Iron Oxide Nanoparticles for Organotropic Drug Targeting.

Biomacromolecules. 2019-2-12

[7]
T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field.

J Nanobiotechnology. 2019-1-22

[8]
Repolarization of myeloid derived suppressor cells via magnetic nanoparticles to promote radiotherapy for glioma treatment.

Nanomedicine. 2018-12-13

[9]
Shape-, size- and structure-controlled synthesis and biocompatibility of iron oxide nanoparticles for magnetic theranostics.

Theranostics. 2018-5-11

[10]
Multi-branched ionic liquid-chitosan as a smart and biocompatible nano-vehicle for combination chemotherapy with stealth and targeted properties.

Carbohydr Polym. 2018-5-18

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