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珠子草中的达玛烷三萜糖苷:化学多样性和生物活性综述。

Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity.

机构信息

Natural Product Chemistry & Process Development, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India.

Natural Product Chemistry & Process Development, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India.

出版信息

Phytochemistry. 2020 Apr;172:112276. doi: 10.1016/j.phytochem.2020.112276. Epub 2020 Feb 12.

Abstract

Bacopa monnieri (L.) is a reputed medicinal herb in traditional system of medicine of India, where it is used as nervine tonic to sharpen intellect and memory. This review discusses chemical characterization of dammarane triterpenoid glycosides which are well accepted for improvement in memory and for potential pharmacological activities. In addition, this review provides information on the chemical composition of specialized metabolites of B. monnieri and in the formulations by different analytical techniques. This comprehensive review covers literature up to 2019 with an emphasis on structural characterization of dammarane triterpenoid glycosides by spectroscopic techniques, chemical composition by analytical methods and pharmacological activities.

摘要

印度传统医学系统中,列当(Bacopa monnieri (L.))是一种著名的药用植物,被用作神经滋补品,以提高智力和记忆力。本文综述了达玛烷三萜糖苷的化学特征,这些糖苷被广泛用于改善记忆和具有潜在的药理活性。此外,本文还介绍了列当的特殊代谢产物的化学组成以及不同分析技术的制剂信息。本综述涵盖了截至 2019 年的文献,重点介绍了达玛烷三萜糖苷的光谱技术结构特征、分析方法的化学组成和药理活性。

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