Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Key Laboratory of Environment and Health, Ministry of Education and Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
J Infect Dis. 2020 Jun 16;222(1):26-33. doi: 10.1093/infdis/jiaa211.
Disease caused by SARS-CoV-2 broke out in Wuhan in December 2019. We utilized confirmed cases outside Hubei Province to analyze epidemiologic characteristics and evaluate the effect of traffic restrictions implemented in Hubei beginning on 23 January 2020.
Information on 7015 confirmed cases from 19 January to 8 February 2020 in all provinces outside Hubei was collected from the national and local health commissions in China. Incubation period and interval times were calculated using dates of the following events: contact with an infected person, onset, first visit, and diagnosis. We evaluated changes in incubation period and interval times.
The average age of all cases was 44.24 years. The median incubation period was 5 days and extended from 2 days on 23 January to 15 days on 8 February. The proportion of imported cases decreased from 85.71% to 33.19% after 23 January. In addition, lengths of intervals between onset and diagnosis, onset and first visit, and first visit and diagnosis decreased over time.
Rapidly transmitting COVID-19 has a short incubation period. The onset mainly occurred among young to middle-aged adults. Traffic restrictions played an important role in the decreased number of imported cases outside Hubei.
2019 年 12 月,SARS-CoV-2 引发的疾病在武汉爆发。我们利用湖北省以外的确诊病例来分析流行病学特征,并评估 2020 年 1 月 23 日开始在湖北省实施的交通限制措施的效果。
从国家和地方卫生委员会收集了 2020 年 1 月 19 日至 2 月 8 日期间中国所有湖北省以外省份的 7015 例确诊病例的信息。潜伏期和间隔时间通过以下事件的日期计算:与感染者接触、发病、首次就诊和诊断。我们评估了潜伏期和间隔时间的变化。
所有病例的平均年龄为 44.24 岁。潜伏期中位数为 5 天,从 1 月 23 日的 2 天延长至 2 月 8 日的 15 天。1 月 23 日后,输入性病例的比例从 85.71%下降至 33.19%。此外,发病与诊断、发病与首次就诊以及首次就诊与诊断之间的间隔时间随时间逐渐缩短。
COVID-19 传播迅速,潜伏期短。发病主要发生在中青年人群。交通限制在湖北省以外输入性病例数量减少方面发挥了重要作用。