Department of Microbiology, University of Medicine 2, Yangon, Yangon, Myanmar.
Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar.
Am J Trop Med Hyg. 2020 Apr;102(4):884-888. doi: 10.4269/ajtmh.19-0725.
The impact of HIV infection on the burden of gastrointestinal pathogens in Myanmar is poorly defined. Stools of 103 HIV-infected and 105 HIV-uninfected adult outpatients at a tertiary referral hospital in Yangon were examined microscopically. Stool antigen tests for infection were positive in 63/103 (61%) HIV-infected and 61/105 (58%) HIV-uninfected patients ( = 0.65). Soil-transmitted helminth infections were much less common, occurring in 9/103 (9%) HIV-infected and 13/103 (13%) HIV-uninfected patients ( = 0.50). One HIV-uninfected patient had , but there were no cases of , , , , , or infection in the entire cohort. Despite the high prevalence of , only 1/208 (0.5%) had ever received eradication, compared with 159/208 (76%) who had ever been dewormed. appears to be an underappreciated pathogen in Myanmar. Its strong association with gastric cancer and peptic ulcer disease necessitates a more aggressive approach to its management.
HIV 感染对缅甸胃肠道病原体负担的影响尚未明确。在仰光的一家三级转诊医院，对 103 名 HIV 感染和 105 名 HIV 未感染的成年门诊患者的粪便进行了检查。103 名 HIV 感染患者中有 63 名（61%）和 105 名 HIV 未感染患者中有 61 名（58%）粪便抗原检测阳性（= 0.65）。感染土壤传播性蠕虫的情况要少见得多，在 103 名 HIV 感染患者中有 9 名（9%）和 103 名 HIV 未感染患者中有 13 名（13%）（= 0.50）。有 1 名 HIV 未感染患者患有 ，但整个队列中均未发现 、 、 、 、 或 感染。尽管 感染的患病率很高，但只有 1/208（0.5%）的患者曾经接受过根除治疗，而 159/208（76%）的患者曾经接受过驱虫治疗。似乎是缅甸被低估的病原体。它与胃癌和消化性溃疡病密切相关，需要更积极地治疗。
