HIV 状态对缅甸仰光胃肠道病原体负担和临床表现的影响。
The Influence of HIV Status on the Burden and Clinical Manifestations of Gastrointestinal Pathogens in Yangon, Myanmar.
机构信息
Department of Microbiology, University of Medicine 2, Yangon, Yangon, Myanmar.
Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar.
出版信息
Am J Trop Med Hyg. 2020 Apr;102(4):884-888. doi: 10.4269/ajtmh.19-0725.
The impact of HIV infection on the burden of gastrointestinal pathogens in Myanmar is poorly defined. Stools of 103 HIV-infected and 105 HIV-uninfected adult outpatients at a tertiary referral hospital in Yangon were examined microscopically. Stool antigen tests for infection were positive in 63/103 (61%) HIV-infected and 61/105 (58%) HIV-uninfected patients ( = 0.65). Soil-transmitted helminth infections were much less common, occurring in 9/103 (9%) HIV-infected and 13/103 (13%) HIV-uninfected patients ( = 0.50). One HIV-uninfected patient had , but there were no cases of , , , , , or infection in the entire cohort. Despite the high prevalence of , only 1/208 (0.5%) had ever received eradication, compared with 159/208 (76%) who had ever been dewormed. appears to be an underappreciated pathogen in Myanmar. Its strong association with gastric cancer and peptic ulcer disease necessitates a more aggressive approach to its management.
HIV 感染对缅甸胃肠道病原体负担的影响尚未明确。在仰光的一家三级转诊医院，对 103 名 HIV 感染和 105 名 HIV 未感染的成年门诊患者的粪便进行了检查。103 名 HIV 感染患者中有 63 名（61%）和 105 名 HIV 未感染患者中有 61 名（58%）粪便抗原检测阳性（= 0.65）。感染土壤传播性蠕虫的情况要少见得多，在 103 名 HIV 感染患者中有 9 名（9%）和 103 名 HIV 未感染患者中有 13 名（13%）（= 0.50）。有 1 名 HIV 未感染患者患有 ，但整个队列中均未发现 、 、 、 、 或 感染。尽管 感染的患病率很高，但只有 1/208（0.5%）的患者曾经接受过根除治疗，而 159/208（76%）的患者曾经接受过驱虫治疗。似乎是缅甸被低估的病原体。它与胃癌和消化性溃疡病密切相关，需要更积极地治疗。
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