Lee Donghyun, Park Eun-Yeong, Choi Seongwook, Kim Hyeongsub, Min Jung-Joon, Lee Changho, Kim Chulhong
Departments of Creative IT Engineering, Electrical Engineering, Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH), Pohang 37674, South Korea.
These authors contributed equally to this work.
Biomed Opt Express. 2020 Jan 13;11(2):752-761. doi: 10.1364/BOE.381963. eCollection 2020 Feb 1.
X-ray acoustic imaging is a hybrid biomedical imaging technique that can acoustically monitor X-ray absorption distribution in biological tissues through the X-ray induced acoustic effect. In this study, we developed a 3D volumetric X-ray-induced acoustic computed tomography (XACT) system with a portable pulsed X-ray source and an arc-shaped ultrasound array transducer. 3D volumetric XACT images are reconstructed via the back-projection algorithm, accelerated by a custom-developed graphics processing unit (GPU) software. Compared with a CPU-based software, the GPU software reconstructs an image over 40 times faster. We have successfully acquired 3D volumetric XACT images of various lead targets, and this work shows that the 3D volumetric XACT system can monitor a high-resolution X-ray dose distribution and image X-ray absorbing structures inside biological tissues.
X射线声学成像是一种混合生物医学成像技术,它可以通过X射线诱导的声学效应,对生物组织中的X射线吸收分布进行声学监测。在本研究中,我们开发了一种三维容积式X射线诱导声学计算机断层扫描(XACT)系统,该系统配备了便携式脉冲X射线源和弧形超声阵列换能器。三维容积式XACT图像通过反投影算法重建,并由定制开发的图形处理单元(GPU)软件加速。与基于中央处理器(CPU)的软件相比,GPU软件重建图像的速度快40多倍。我们已成功获取了各种铅靶的三维容积式XACT图像,这项工作表明三维容积式XACT系统能够监测生物组织内部的高分辨率X射线剂量分布,并对X射线吸收结构进行成像。