尘螨过敏患者对虾的致敏情况。
Shrimp sensitization in house dust mite allergic patients.
机构信息
Department of Allergology, Clinical Immunology and Internal Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Department of Obstetrics and Gynecology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
出版信息
Int J Immunopathol Pharmacol. 2020 Jan-Dec;34:2058738420907188. doi: 10.1177/2058738420907188.
Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to and 57.8% to . In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable.
虾肌球蛋白与屋尘螨（HDM）肌球蛋白具有相似的结构。在这项研究中，随机选择了 232 名有持续性过敏性鼻炎症状的成年患者。在该组中，59%对 和 57.8%过敏。共有 128 名（55.2%）患者对两种 HDM 物种均过敏，143 名（61.6%）至少对一种过敏。略超过四分之一（25.4%）的患者对虾过敏。在 35 名虾过敏患者中，发现 11 例（31.4%）对 Der p 10 和 Pen a 1 过敏。Pen a 1 和 Der p 10 的 IgE 浓度之间存在很强的相关性。结果表明，在 HDM 过敏患者中，存在其他过敏原导致虾过敏的高发生率。Der p 10 和 Pen a 1 水平的高度趋同可能表明仅测定其中之一是合理的。
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