Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, Hongshan, Wuhan, 430074, People's Republic of China.
Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Top Curr Chem (Cham). 2020 Mar 7;378(2):31. doi: 10.1007/s41061-020-0292-x.
DNA nanotechnology, based on sequence-specific DNA recognition, could allow programmed self-assembly of sophisticated nanostructures with molecular precision. Extension of this technique to the preparation of broader types of nanomaterials would significantly improve nanofabrication technique to lower nanometer scale and even achieve single molecule operation. Using such exquisite DNA nanostructures as templates, chemical synthesis of polymer and inorganic nanomaterials could also be programmed with unprecedented accuracy and flexibility. This review summarizes recent advances in the synthesis and assembly of polymer and inorganic nanomaterials using DNA nanostructures as templates, and discusses the current challenges and future outlook of DNA templated nanotechnology.
DNA 纳米技术基于序列特异性 DNA 识别，可实现复杂纳米结构的分子级精确编程自组装。将该技术扩展到更广泛类型的纳米材料的制备中，将极大地改善纳米制造技术，降低纳米尺度，甚至实现单分子操作。利用这种精密的 DNA 纳米结构作为模板，也可以以前所未有的精度和灵活性来对聚合物和无机纳米材料的化学合成进行编程。本文综述了利用 DNA 纳米结构作为模板合成和组装聚合物和无机纳米材料的最新进展，并讨论了 DNA 模板纳米技术的当前挑战和未来展望。
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