Department of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.
Wyss Institute for Biologically Inspired Engineering, Harvard University , Boston, Massachusetts 02115, United States.
ACS Nano. 2017 Jan 24;11(1):227-238. doi: 10.1021/acsnano.6b04777. Epub 2017 Jan 10.
This paper describes the fabrication of polymer stamps using DNA nanostructure templates. This process creates stamps having diverse nanoscale features with dimensions ranging from several tens of nanometers to micrometers. DNA nanostructures including DNA nanotubes, stretched λ-DNA, two-dimensional (2D) DNA brick crystals with three-dimensional (3D) features, hexagonal DNA 2D arrays, and triangular DNA origami were used as master templates to transfer patterns to poly(methyl methacrylate) and poly(l-lactic acid) with high fidelity. The resulting polymer stamps were used as molds to transfer the pattern to acryloxy perfluoropolyether polymer. This work establishes an approach to using self-assembled DNA templates for applications in soft lithography.
本文描述了使用 DNA 纳米结构模板制作聚合物印章的方法。该工艺可制作具有从几十纳米到几微米等不同纳米尺寸特征的印章。DNA 纳米结构，包括 DNA 纳米管、拉伸的 λ-DNA、具有三维（3D）特征的二维（2D）DNA 砖晶体、六方 DNA 二维阵列和三角形 DNA 折纸，被用作母版，以高精度将图案转印到聚甲基丙烯酸甲酯和聚 L-乳酸上。所得聚合物印章被用作模具，将图案转印到丙烯氧基全氟聚醚聚合物上。这项工作建立了一种使用自组装 DNA 模板的方法，可应用于软光刻技术。
