Rehabilitation Services, Periphery Hospitals, Ministry of Health, Manama, Bahrain.
College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
Eur J Nutr. 2020 Sep;59(6):2291-2316. doi: 10.1007/s00394-020-02216-1. Epub 2020 Mar 10.
Studies on the effect of Ramadan diurnal intermittent fasting (RDIF) on body weight have yielded conflicting results. Therefore, we conducted a systematic review and meta-analysis to estimate the effect size of body weight changes in healthy, non-athletic Muslims practicing Ramadan fasting, and to assess the effect of covariates such as age, sex, fasting time duration, season, and country, using subgroup analysis, and meta-regression. Covariate adjustments were performed to explain the variability of weight change in response to Ramadan fasting.
CINAHL, Cochrane, EBSCOhost, EMBASE, Google Scholar, ProQuest Medical, PubMed/MEDLINE, ScienceDirect, Scopus, and Web of Science databases were searched from date of inception in 1950 to the end of August 2019.
Eighty-five studies, conducted in 25 countries during 1982-2019, were identified. RDIF yielded a significant, but small reduction in body weight (K = 85, number of subjects, N = 4176 (aged 16-80 years), Hedges' g =- 0.360, 95% confidence interval (CI) - 0.405 to - 0.315, I = 45.6%), this effect size translates into difference in means of - 1.022 kg (95% CI - 1.164 kg to - 0.880 kg). Regression analysis for moderator covariates revealed that fasting time (min/day) is a significant (P < 0.05) moderator for weight change at the end of Ramadan, while age and sex are not. Variable effects for the season and country were found.
RDIF may confer a significant small reduction in body weight in non-athletic healthy people aged 16 years and above, directly associated with fasting time and variably correlated with the season, and country.
关于斋月日间间歇性禁食（RDIF）对体重影响的研究结果相互矛盾。因此，我们进行了系统评价和荟萃分析，以估计在健康、非运动的穆斯林中进行斋月禁食时体重变化的效应大小，并使用亚组分析和荟萃回归评估年龄、性别、禁食时间、季节和国家等协变量的影响。进行协变量调整以解释对斋月禁食的体重变化的可变性。
从 1950 年的成立日期到 2019 年 8 月底，在 CINAHL、Cochrane、EBSCOhost、EMBASE、Google Scholar、ProQuest Medical、PubMed/MEDLINE、ScienceDirect、Scopus 和 Web of Science 数据库中进行了搜索。
共确定了 85 项研究，这些研究在 2019 年期间在 25 个国家进行。RDIF 导致体重显著但较小的下降（K=85，研究数量，N=4176（年龄 16-80 岁），Hedges'g=-0.360，95%置信区间（CI）-0.405 至-0.315，I=45.6%），该效应大小转化为平均值的差异-1.022kg（95%CI-1.164kg 至-0.880kg）。协变量调节分析表明，禁食时间（分钟/天）是斋月结束时体重变化的重要（P<0.05）调节因素，而年龄和性别不是。还发现了季节和国家的变量效应。
RDIF 可能会使 16 岁及以上非运动健康人群的体重显著减轻，这与禁食时间直接相关，并与季节和国家的变化相关。
