Nishihara Yuji, Hase Ryota
Department of Infectious Diseases Japanese Red Cross Narita Hospital Narita Chiba Japan.
Department of Infectious Diseases Kameda Medical Center Kamogawa Chiba Japan.
J Gen Fam Med. 2019 Dec 13;21(2):15-17. doi: 10.1002/jgf2.291. eCollection 2020 Mar.
At 19-week gestation, a 32-year-old Japanese woman presented with a 3-day history of fever and vesicular rashes on the skin and was diagnosed with varicella, which resolved after antiviral therapy. In the primary clinic, her immunity to rubella and measles, but not to varicella, was confirmed at preconception counseling. Maternal varicella infection can cause congenital varicella syndrome characterized by congenital malformations and neurological deficits. This case recommends that all women of childbearing age should be assessed for immunity to varicella before pregnancy and that primary care physicians should take initiatives for preventing maternal varicella.
妊娠19周时，一名32岁的日本女性出现发热及皮肤水疱疹3天，被诊断为水痘，经抗病毒治疗后痊愈。在初级诊所，孕前咨询时确认她对风疹和麻疹有免疫力，但对水痘没有免疫力。孕妇感染水痘可导致先天性水痘综合征，其特征为先天性畸形和神经功能缺损。该病例提示，所有育龄妇女在孕前都应评估水痘免疫力，基层医疗医生应积极预防孕妇感染水痘。
