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[具体药物名称]软膏对初产妇会阴侧切伤口的愈合效果。 (你提供的原文中“and”处应该有具体药物名称等信息缺失,我按照正常逻辑补充了[具体药物名称])

Healing effect of and ointment on episiotomy wounds in primiparous women.

作者信息

Zibanejad Sanaz, Miraj Sepideh, Rafieian Kopaei Mahmoud

机构信息

Departments of Obstetrics and Gynecology, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Departments of Obstetrics and Gynecology, Infertility Fellowship, Shahrekord University of Medical Sciences, Shahrekord, Iran.

出版信息

J Res Med Sci. 2020 Feb 20;25:11. doi: 10.4103/jrms.JRMS_251_18. eCollection 2020.

DOI:10.4103/jrms.JRMS_251_18
PMID:32174983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7053167/
Abstract

BACKGROUND

Episiotomy is one of the most common surgical interventions performed to facilitate delivery. Anti-inflammatory and antibacterial effects of Persian oak () and henna () have been proved in previous studies. The aim of this study is to evaluate the effect of and ointment on episiotomy wound healing in primiparous women and comparing it with placebo group.

MATERIALS AND METHODS

This was a double-blind clinical trial conducted on 160 primiparous women who underwent episiotomy. The cases were randomly selected and divided into four groups of forty patients including control, placebo, those who consume topical henna, and those who consume topical Persian oak ointment. Pain and recovery assessment was done at baseline and 7, 10, and 14 days after birth and measured by Redness, Edema, Ecchymosis, Discharge, and Approximation (REEDA scale) and patients' pain intensity was also measured by a visual analog scale (VAS). The collected data were analyzed using Chi-square test, one-way ANOVA, and repeated measures ANOVA test by SPSS (version 22).

RESULTS

The results revealed that according to the reduced score of REEDA till the 14 day after the delivery, the wound healing in the henna group and the oak group (-2.58 ± 0.29 and - 2.04 ± 0.31, respectively) was higher than the control and placebo groups (-1.62 ± 0.34 and - 1.95 ± 0.32, respectively) ( < 0.05). Furthermore, on the 14 day, the mean VAS score was not significantly different between henna and oak groups (henna group: 2.58 ± 0.25 and oak group: 2.23 ± 0.18); however, both intervention groups had a significant difference with the placebo and control groups ( < 0.05).

CONCLUSION

The findings showed that the use of henna and oak ointment improves episiotomy wound healing process, so it is recommended for primiparous women.

摘要

背景

会阴切开术是为方便分娩而进行的最常见的外科手术干预措施之一。此前的研究已证实波斯橡树()和指甲花()具有抗炎和抗菌作用。本研究旨在评估指甲花和波斯橡树软膏对初产妇会阴切开术伤口愈合的影响,并与安慰剂组进行比较。

材料与方法

这是一项针对160例行会阴切开术的初产妇进行的双盲临床试验。将病例随机选取并分为四组,每组40例患者,包括对照组、安慰剂组、使用外用指甲花的组和使用外用波斯橡树软膏的组。在基线以及产后7天、10天和14天进行疼痛和恢复评估,通过发红、水肿、瘀斑、分泌物和切口愈合情况(REEDA量表)进行测量,患者的疼痛强度也通过视觉模拟量表(VAS)进行测量。使用SPSS(22版)通过卡方检验、单因素方差分析和重复测量方差分析对收集的数据进行分析。

结果

结果显示,根据产后14天REEDA评分的降低情况,指甲花组和橡树组(分别为-2.58±0.29和-2.04±0.31)的伤口愈合情况高于对照组和安慰剂组(分别为-1.62±0.34和-1.95±0.32)(<0.05)。此外,在第14天,指甲花组和橡树组的平均VAS评分无显著差异(指甲花组:2.58±0.25,橡树组:2.23±0.18);然而,两个干预组与安慰剂组和对照组均有显著差异(<0.05)。

结论

研究结果表明,使用指甲花和橡树软膏可改善会阴切开术伤口的愈合过程,因此推荐给初产妇。

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