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本文引用的文献

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Inhibition of COX-2 and EGFR by Melafolone Improves Anti-PD-1 Therapy through Vascular Normalization and PD-L1 Downregulation in Lung Cancer.美拉诺醇通过抑制 COX-2 和 EGFR 促进血管正常化和下调 PD-L1 改善肺癌的抗 PD-1 治疗。
J Pharmacol Exp Ther. 2019 Mar;368(3):401-413. doi: 10.1124/jpet.118.254359. Epub 2018 Dec 27.
2
Madhuca indica Inhibits Breast Cancer Cell Proliferation by Modulating COX-2 Expression.印度麻槿通过调节 COX-2 表达抑制乳腺癌细胞增殖。
Curr Mol Med. 2018;18(7):459-474. doi: 10.2174/1566524019666181212100808.
3
Revisiting the Concept of Targeting NFAT to Control T Cell Immunity and Autoimmune Diseases.重新审视靶向 NFAT 以控制 T 细胞免疫和自身免疫性疾病的概念。
Front Immunol. 2018 Nov 27;9:2747. doi: 10.3389/fimmu.2018.02747. eCollection 2018.
4
The role of CXC chemokine ligand 4/CXC chemokine receptor 3-B in breast cancer progression.CXC趋化因子配体4/CXC趋化因子受体3-B在乳腺癌进展中的作用。
Biotech Histochem. 2019 Jan;94(1):53-59. doi: 10.1080/10520295.2018.1497201. Epub 2018 Sep 28.
5
Correlation of COX-2 and MMP-13 expressions with gastric cancer and their effects on prognosis.COX-2与MMP-13表达与胃癌的相关性及其对预后的影响。
J BUON. 2018 May-Jun;23(3):665-671.
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Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation.蜗牛通过上调 CXCR2 配体招募髓源抑制性细胞促进卵巢癌进展。
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Green tea polyphenols affect invasiveness of human gastric MKN-28 cells by inhibition of LPS or TNF-α induced Matrix Metalloproteinase-9/2.绿茶多酚通过抑制脂多糖或肿瘤坏死因子-α诱导的基质金属蛋白酶-9/2来影响人胃癌MKN-28细胞的侵袭性。
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Cytokine. 2018 Apr;104:114-123. doi: 10.1016/j.cyto.2017.10.004. Epub 2017 Oct 9.

基质金属蛋白酶、炎症和癌症的三位一体：最新文献综述。

The Trinity of Matrix Metalloproteinases, Inflammation, and Cancer: A Literature Review of Recent Updates.

机构信息

Department of Biochemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey.

出版信息

Antiinflamm Antiallergy Agents Med Chem. 2020;19(3):206-221. doi: 10.2174/1871523018666191023141807.

DOI:10.2174/1871523018666191023141807
PMID:32178620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7499348/
Abstract

The critical link between cancer and inflammation has been known for many years. This complex network was further complexed by revealing the association of the matrix metalloproteinase family members with inflammatory cytokines, which were previously known to be responsible for the development of metastasis. This article summarizes the current studies which evaluate the relationship between cancer and inflammatory microenvironment as well as the roles of MMPs on invasion and metastasis together.

摘要

多年来，人们已经认识到癌症和炎症之间的关键联系。通过揭示基质金属蛋白酶家族成员与先前已知负责转移发展的炎症细胞因子之间的关联，这一复杂网络变得更加复杂。本文总结了目前评估癌症与炎症微环境之间关系的研究，以及 MMPs 在侵袭和转移中的作用。