National Center for Wellness and Recovery, Oklahoma State University Center for Health Sciences, Tulsa, USA.
Department of Rural Health, Oklahoma State University Center for Health Sciences, Stillwater, USA.
Drug Alcohol Rev. 2021 Nov;40(7):1143-1154. doi: 10.1111/dar.13045. Epub 2020 Mar 17.
Transdermal alcohol sensors allow objective, continuous monitoring and have potential to expand current research on adolescent and young adult alcohol use. The purpose of this manuscript is to evaluate the feasibility and reliability of transdermal alcohol sensor use among female adolescents as compared to female young adults.
This trial included 59 female adolescents and young adults aged 14-24 years who reported drinking during the previous month. All participants were asked to wear a Giner Wrist Transdermal Alcohol Sensor (WrisTAS)-7 over a 1 month prospective study. Participants came to the research lab weekly to complete a detailed self-report of behaviours, including day of drinking events, amounts and types of alcohol use and length of drinking events. Estimates of blood alcohol concentration (eBAC) were computed from self-report data using the Matthew and Miller, NHTSA and Zhang equations. Daily transdermal alcohol concentration (TAC) peaks and calculated eBAC peak data were analysed with paired-samples t-tests and repeated measures correlations for validity comparisons.
All participants (100%, n = 59) completed the trial, however, two participants were removed due to greater than 50% of missing transdermal alcohol sensor data. Of the 57 participants, the data included 1,722 days of continuous alcohol monitoring. Missing data was recorded more frequently among female adolescents at about (11.78%) as compared to female young adults (8.59%; χ = -18.40, P < 0.001). Participant self-report of drinking occurred with greater frequency (374 events) than detected by the WrisTAS transdermal alcohol sensors (243 events). On days when self-report and sensor data indicated a drinking event, participants' eBAC was moderately correlated with TAC, after accounting for repeated measures.
This study finds that transdermal alcohol sensors are moderately reliable when sensor data is paired with self-report. This objective data collection method may improve the ability to collect alcohol curves among adolescents.
经皮酒精传感器可实现客观、连续监测，并有潜力拓展当前对青少年和年轻成年人饮酒的研究。本文旨在评估经皮酒精传感器在女性青少年中的使用可行性和可靠性，并与女性年轻成年人进行比较。
本试验纳入了 59 名年龄在 14-24 岁之间、过去一个月有饮酒行为的女性青少年和年轻成年人。所有参与者均被要求佩戴 Giner WrisTAS-7 经皮酒精传感器（WrisTAS）进行为期 1 个月的前瞻性研究。参与者每周来研究实验室完成详细的行为自我报告，包括饮酒日、饮酒量和类型以及饮酒时长。使用 Matthew 和 Miller、NHTSA 和 Zhang 方程，根据自我报告数据估算血酒精浓度（eBAC）。使用配对样本 t 检验和重复测量相关性分析，对每日经皮酒精浓度（TAC）峰值和计算的 eBAC 峰值数据进行分析，以进行有效性比较。
所有参与者（100%，n=59）均完成了试验，但由于经皮酒精传感器数据缺失超过 50%，有两名参与者被排除。在 57 名参与者中，数据包含 1722 天连续的酒精监测。与女性年轻成年人（8.59%；χ²=-18.40，P<0.001）相比，女性青少年的缺失数据记录频率更高（11.78%）。参与者自我报告的饮酒事件比 WrisTAS 经皮酒精传感器检测到的更频繁（374 次事件比 243 次事件）。当自我报告和传感器数据均表明有饮酒事件发生时，参与者的 eBAC 与 TAC 呈中度相关，在考虑重复测量后。
本研究发现，当传感器数据与自我报告相结合时，经皮酒精传感器具有中等可靠性。这种客观的数据收集方法可能会提高在青少年中收集酒精曲线的能力。
