Department of Surgery, University of California, Irvine, Orange, 92868 CA, USA.
Department of Surgery, University of California, Irvine, Orange, 92868 CA, USA; Department of Food Hygiene and Consumer Health Protection, Wroclaw University of Environmental and Life Sciences, 50-375, Wroclaw, Poland.
J Microbiol Immunol Infect. 2020 Jun;53(3):454-458. doi: 10.1016/j.jmii.2020.03.013. Epub 2020 Mar 14.
With its epicenter in Wuhan, China, the COVID-19 outbreak was declared a pandemic by the World Health Organization (WHO). While many countries have implemented flight restrictions to China, an increasing number of cases with or without travel background to China are confirmed daily. These developments support concerns on possible unidentified and unreported international COVID-19 cases, which could lead to new local disease epicenters.
We have analyzed all available data on the development of international COVID-19 cases from January 20th, 2020 until February 18th, 2020. COVID-19 cases with and without travel history to China were divided into cohorts according to the Healthcare Access and Quality Index (HAQ-Index) of each country. Chi-square and Post-hoc testing were performed.
While COVID-19 cases with travel history to China seem to peak for each HAQ-cohort, the number of non-travel related COVID-19 cases seem to continuously increase in the HAQ-cohort of countries with higher medical standards. Further analyses demonstrate a significantly lower proportion of reported COVID-19 cases without travel history to China in countries with lower HAQ (HAQ I vs. HAQ II, posthoc p < 0.01).
Our data indicate that countries with lower HAQ-index may either underreport COVID-19 cases or are unable to adequately detect them. Although our data may be incomplete and must be interpreted with caution, inconsistencies in reporting COVID-19 cases is a serious problem which might sabotage efforts to contain the virus.
新冠疫情以中国武汉为中心爆发,世界卫生组织(WHO)宣布其为大流行。虽然许多国家对中国实施了航班限制,但每日仍有越来越多的确诊病例,无论是否有中国旅行史。这些发展情况令人担忧,可能存在未被识别和报告的国际新冠病例,这可能导致新的本地疾病中心。
我们分析了 2020 年 1 月 20 日至 2 月 18 日期间所有关于国际新冠病例发展的可用数据。根据各国的医疗保健可及性和质量指数(HAQ-Index),将有和无中国旅行史的新冠病例分为两组。进行了卡方检验和事后检验。
虽然有中国旅行史的新冠病例似乎在每个 HAQ 组中达到高峰,但在医疗标准较高的国家中,与旅行无关的新冠病例数量似乎在不断增加。进一步的分析表明,HAQ 较低的国家报告的无中国旅行史新冠病例比例明显较低(HAQ I 与 HAQ II 相比,事后检验 p<0.01)。
我们的数据表明,HAQ 指数较低的国家可能要么漏报新冠病例,要么无法充分检测到它们。尽管我们的数据可能不完整,必须谨慎解释,但不一致的新冠病例报告是一个严重的问题,可能会破坏遏制病毒的努力。