Rahko T, Saloniemi H, Kalima T V
Acta Vet Scand. 1988;29(2):255-8. doi: 10.1186/BF03548379.
Ultrastructural alterations of pancreatic tissues in growing pigs caused by surgical ligation of the main pancreatic duct are described. Five animals aged 6 to 7 weeks were operated on and necropsied 2, 6 or 8 weeks later. In addition, 3 pigs that were sham-operated served as controls. Obstruction of the ducts caused progressive luminal dilatations and rupture of intercellular connections of the epithelium followed by destruction and atrophy of acinar parenchyma and proliferations of immature ductular epithelial cells free from zymogen granules.
描述了通过手术结扎猪的主胰管对生长猪胰腺组织造成的超微结构改变。对5只6至7周龄的动物进行手术，并在2、6或8周后进行尸检。此外，3只假手术的猪作为对照。导管阻塞导致管腔逐渐扩张，上皮细胞间连接破裂，随后腺泡实质破坏和萎缩，以及无酶原颗粒的未成熟导管上皮细胞增殖。
