再生医学在器官移植中的出现：第 1 届欧洲细胞治疗和器官再生分会会议。
The emergence of regenerative medicine in organ transplantation: 1st European Cell Therapy and Organ Regeneration Section meeting.
机构信息
Department of Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Technology (BIST), Barcelona, Spain.
出版信息
Transpl Int. 2020 Aug;33(8):833-840. doi: 10.1111/tri.13608. Epub 2020 Apr 28.
Abstract
Regenerative medicine is emerging as a novel field in organ transplantation. In September 2019, the European Cell Therapy and Organ Regeneration Section (ECTORS) of the European Society for Organ Transplantation (ESOT) held its first meeting to discuss the state-of-the-art of regenerative medicine in organ transplantation. The present article highlights the key areas of interest and major advances in this multidisciplinary field in organ regeneration and discusses its implications for the future of organ transplantation.
摘要
再生医学正在成为器官移植领域的一个新兴领域。2019 年 9 月，欧洲器官移植学会（ESOT）细胞治疗和器官再生分会（ECTORS）举行了第一次会议，讨论了器官移植中再生医学的最新进展。本文重点介绍了器官再生这一多学科领域的主要关注点和主要进展，并探讨了其对器官移植未来的影响。
相似文献
1
The emergence of regenerative medicine in organ transplantation: 1st European Cell Therapy and Organ Regeneration Section meeting.再生医学在器官移植中的出现：第 1 届欧洲细胞治疗和器官再生分会会议。
Transpl Int. 2020 Aug;33(8):833-840. doi: 10.1111/tri.13608. Epub 2020 Apr 28.
2
Will regenerative medicine replace transplantation?再生医学是否会取代移植？
Cold Spring Harb Perspect Med. 2013 Aug 1;3(8):a015693. doi: 10.1101/cshperspect.a015693.
3
Emerging technologies in organ preservation, tissue engineering and regenerative medicine: a blessing or curse for transplantation?器官保存、组织工程和再生医学领域的新兴技术：对移植来说是福是祸？
Transpl Int. 2019 Jul;32(7):673-685. doi: 10.1111/tri.13432. Epub 2019 Apr 11.
4
Transforming organ transplantation with regenerative medicine: an interview with Giuseppe Orlando.用再生医学变革器官移植：对朱塞佩·奥兰多的采访
Regen Med. 2024 Jan;19(1):5-6. doi: 10.2217/rme-2023-0204. Epub 2023 Nov 13.
5
Functional ectodermal organ regeneration as the next generation of organ replacement therapy.功能性外胚层器官再生——下一代器官替代疗法。
Open Biol. 2019 Mar 29;9(3):190010. doi: 10.1098/rsob.190010.
6
Cellular therapies in organ transplantation.器官移植中的细胞治疗。
Transpl Int. 2021 Feb;34(2):233-244. doi: 10.1111/tri.13789. Epub 2021 Jan 15.
7
Advances in hydrogel delivery systems for tissue regeneration.用于组织再生的水凝胶递送系统的进展。
Mater Sci Eng C Mater Biol Appl. 2014 Dec;45:690-7. doi: 10.1016/j.msec.2014.04.026. Epub 2014 Apr 16.
8
Organ regeneration based on developmental biology: past and future.基于发育生物学的器官再生：过去和未来。
Curr Opin Genet Dev. 2018 Oct;52:42-47. doi: 10.1016/j.gde.2018.05.008. Epub 2018 Jun 5.
9
[Fully functional salivary gland regeneration as a next-generation regenerative therapy].[全功能唾液腺再生作为下一代再生疗法]
Nihon Rinsho Meneki Gakkai Kaishi. 2015;38(2):93-100. doi: 10.2177/jsci.38.93.
10
The future of replacement and restorative therapies: from organ transplantation to regenerative medicine.替代与修复疗法的未来：从器官移植到再生医学。
Transplant Proc. 2013;45(10):3450-2. doi: 10.1016/j.transproceed.2013.09.011.
引用本文的文献
1
Stem Cells in Regenerative Medicine: A Journey from Adult Stem Cells to Induced Pluripotent Cells.再生医学中的干细胞：从成体干细胞到诱导多能干细胞的历程。
Int J Mol Sci. 2025 Aug 26;26(17):8255. doi: 10.3390/ijms26178255.
2
Advances in Drug Delivery Integrated with Regenerative Medicine: Innovations, Challenges, and Future Frontiers.药物递送与再生医学整合的进展：创新、挑战与未来前沿。
Pharmaceutics. 2025 Apr 1;17(4):456. doi: 10.3390/pharmaceutics17040456.
3
A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors.一项在小型和大型动物模型中进行的概念验证研究，旨在将肝脏常温机器灌注与间充质基质细胞生物反应器相结合。
Nat Commun. 2025 Jan 2;16(1):283. doi: 10.1038/s41467-024-55217-7.
4
Dynamic conditioning of porcine kidney grafts with extracellular vesicles derived from urine progenitor cells: A proof-of-concept study.用尿祖细胞衍生的细胞外囊泡对猪肾移植物进行动态预处理：一项概念验证研究。
Clin Transl Med. 2024 Dec;14(12):e70095. doi: 10.1002/ctm2.70095.
5
Stem Cell-Derived Extracellular Vesicles in the Treatment of Cardiovascular Diseases.干细胞衍生的细胞外囊泡在心血管疾病治疗中的应用
Pharmaceutics. 2024 Mar 11;16(3):381. doi: 10.3390/pharmaceutics16030381.
6
Organ Repair and Regeneration During Dynamic Preservation: The Future is Nano.动态保存过程中的器官修复和再生：未来是纳米的。
Transpl Int. 2023 Nov 10;36:11947. doi: 10.3389/ti.2023.11947. eCollection 2023.
7
Decellularized Extracellular Matrix: The Role of This Complex Biomaterial in Regeneration.去细胞化细胞外基质：这种复杂生物材料在再生中的作用。
ACS Omega. 2023 Jun 14;8(25):22256-22267. doi: 10.1021/acsomega.2c06216. eCollection 2023 Jun 27.
8
New Perspectives for Postmortem Human Satellite Cells of Different Embryological Origin.不同胚胎起源的人死后卫星细胞的新视角。
Front Physiol. 2022 May 25;13:886149. doi: 10.3389/fphys.2022.886149. eCollection 2022.
9
How to Make Sense out of 75,000 Mesenchymal Stromal Cell Publications?如何从 75000 篇间充质基质细胞文献中理出头绪？
Cells. 2022 Apr 22;11(9):1419. doi: 10.3390/cells11091419.
10
Creation and use of organoids in biomedical research and healthcare: the bioethical and metabioethical issues.生物医学研究和医疗保健中类器官的创建和使用：生物伦理和代谢生物伦理问题。
Cell Adh Migr. 2021 Dec;15(1):285-294. doi: 10.1080/19336918.2021.1996749.
本文引用的文献
1
Potential Applications of Extracellular Vesicles in Solid Organ Transplantation.细胞外囊泡在实体器官移植中的潜在应用。
Cells. 2020 Feb 5;9(2):369. doi: 10.3390/cells9020369.
2
Fast, robust and effective decellularization of whole human livers using mild detergents and pressure controlled perfusion.使用温和的清洁剂和压力控制灌注快速、稳健且有效地去除整个人类肝脏的细胞。
Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:110200. doi: 10.1016/j.msec.2019.110200. Epub 2019 Sep 12.
3
Kidney transplant tolerance associated with remote autologous mesenchymal stromal cell administration.与远程自体间充质基质细胞给药相关的肾移植耐受
Stem Cells Transl Med. 2020 Apr;9(4):427-432. doi: 10.1002/sctm.19-0185. Epub 2019 Dec 24.
4
Bone marrow-derived mesenchymal stromal cell treatment in patients with ischaemic heart failure: final 4-year follow-up of the MSC-HF trial.缺血性心力衰竭患者的骨髓间充质基质细胞治疗：MSC-HF试验的4年最终随访
Eur J Heart Fail. 2020 May;22(5):884-892. doi: 10.1002/ejhf.1700. Epub 2019 Dec 21.
5
Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells.大规模生产 LGR5 阳性的人肝干细胞双潜能细胞。
Hepatology. 2020 Jul;72(1):257-270. doi: 10.1002/hep.31037. Epub 2020 Apr 8.
6
Autologous adipose-derived stromal cell treatment for patients with refractory angina (MyStromalCell Trial): 3-years follow-up results.自体脂肪来源的基质细胞治疗难治性心绞痛（MyStromalCell 试验）：3 年随访结果。
J Transl Med. 2019 Nov 12;17(1):360. doi: 10.1186/s12967-019-2110-1.
7
First Report on Ex Vivo Delivery of Paracrine Active Human Mesenchymal Stromal Cells to Liver Grafts During Machine Perfusion.关于在机器灌注期间将旁分泌活性人骨髓间充质基质细胞体外输送至肝移植供肝的首次报告。
Transplantation. 2020 Jan;104(1):e5-e7. doi: 10.1097/TP.0000000000002986.
8
Infusing Mesenchymal Stromal Cells into Porcine Kidneys during Normothermic Machine Perfusion: Intact MSCs Can Be Traced and Localised to Glomeruli.在常温机器灌注期间将间充质基质细胞注入猪肾脏：完整的 MSC 可被追踪并定位于肾小球。
Int J Mol Sci. 2019 Jul 23;20(14):3607. doi: 10.3390/ijms20143607.
9
Mesenchymal Stromal Cells Are Retained in the Porcine Renal Cortex Independently of Their Metabolic State After Renal Intra-Arterial Infusion.间质基质细胞在经肾内动脉输注后，其代谢状态独立于肾皮质而被保留。
Stem Cells Dev. 2019 Sep 15;28(18):1224-1235. doi: 10.1089/scd.2019.0105. Epub 2019 Aug 1.
10
Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients.分析异体脂肪间充质干细胞局部给药后对克罗恩病肛周瘘患者的同种异体致敏作用。
Front Immunol. 2019 Jun 14;10:1244. doi: 10.3389/fimmu.2019.01244. eCollection 2019.
Zotero 插件