Yu Junke, Zhao Zhihui, Sun Jianxin, Geng Cunzhen, Bu Qingxu, Wu Dawei, Xia Yanzhi
State Key Laboratory of Bio-Fibers and Eco-Textiles, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Institute of Marine Biobased Materials, Qingdao University, Qingdao 266071, China.
School of Material Science and Engineering, Qingdao University, Qingdao 266071, China.
Nanomaterials (Basel). 2020 Mar 20;10(3):565. doi: 10.3390/nano10030565.
In this study, sodium alginate (SA) nanofibres were obtained by electrospinning via the assistance of traditional poly(ethyl oxide) (PEO) and dimethyl sulfoxide (DMSO) with a high SA/PEO ratio of up to 94:6. However, surfactants with more or less toxicities were replaced by nontoxic and fluorescent carbon dots (CDs) to improve spinnability. Experimental details were conducted by fixing the ratio of SA/PEO to 90:10. Then, the electrospinning products of solutions with different compositions were observed with scanning electron microscopy. Properties such as conductivity, surface tension and rheology of the solutions were investigated to determine the key influencing factors. Moreover, since CDs have excellent fluorescence properties, the fluorescent properties of the nanofibre membrane that was blended with CDs were then collected. In addition, in vitro cytotoxicity assessment of the nanofibres were conducted to evaluate the toxicities and biocompatibility.
在本研究中，海藻酸钠（SA）纳米纤维是通过静电纺丝法，在传统的聚环氧乙烷（PEO）和二甲基亚砜（DMSO）的辅助下获得的，SA与PEO的比例高达94:6。然而，具有或多或少毒性的表面活性剂被无毒且具有荧光的碳点（CDs）所取代，以提高可纺性。通过将SA/PEO的比例固定为90:10来进行实验细节。然后，用扫描电子显微镜观察不同组成溶液的静电纺丝产物。研究了溶液的电导率、表面张力和流变学等性质，以确定关键影响因素。此外，由于碳点具有优异的荧光特性，随后收集了与碳点共混的纳米纤维膜的荧光特性。此外，还对纳米纤维进行了体外细胞毒性评估，以评估其毒性和生物相容性。
