Dublin Dental University Hospital, Trinty College Dublin, Dublin, Ireland.
Blekinge Institute of Technology, Karlskrona, Sweden.
J Clin Periodontol. 2020 Jun;47(6):715-725. doi: 10.1111/jcpe.13287. Epub 2020 Apr 21.
To investigate whether there was an association between periodontitis and airflow limitation in older Swedish individuals.
Study individuals were randomly selected from the Swedish civil registration database representing the ageing population in Karlskrona, Sweden. Clinical and radiographic examinations were performed, alongside which participants completed questionnaires gathering information on their medical history, social circumstances, demographic background and tobacco use. A physical examination assessed anthropometric measures. Standard spirometry was performed to identify subjects with airflow limitation. Periodontitis was defined based on radiographic periodontal bone loss. Analysis included multiple logistic regression with adjustment for various confounders.
A total of 826 Caucasian dentate subjects were included in the analysis. The median age of participants was 73.2 (IQR 66-81) years, and 443 (54.6%) subjects were female. Eighty-six (10.4%) individuals presented with airflow limitation. The proportion of participants presenting with periodontitis in the airflow limitation group was 65.1% compared to 41.5% with normal respiratory function (p < .001). Multiple logistic regression analysis showed that periodontitis was independently associated with airflow limitation with an odds ratio of 2.31 (95% CI 1.27-4.22) p < .01.
In this group of older dentate individuals, periodontitis was significantly associated with airflow limitation independent of other known risk factors.
调查牙周炎与老年瑞典人群气流受限之间是否存在关联。
研究对象是从代表瑞典卡尔斯克鲁纳老龄化人口的瑞典公民登记数据库中随机选择的。进行了临床和影像学检查，同时参与者完成了问卷调查，收集了他们的病史、社会情况、人口统计学背景和吸烟习惯的信息。体格检查评估了人体测量学指标。进行标准肺活量测定以确定气流受限的受试者。牙周炎的定义基于放射影像学牙周骨丧失。分析包括调整各种混杂因素后的多变量逻辑回归。
共纳入 826 名白种牙列完整的受试者进行分析。参与者的中位年龄为 73.2（IQR 66-81）岁，443 名（54.6%）为女性。86 名（10.4%）患者存在气流受限。在气流受限组中，牙周炎患者的比例为 65.1%，而呼吸功能正常的患者比例为 41.5%（p<0.001）。多变量逻辑回归分析表明，牙周炎与气流受限独立相关，优势比为 2.31（95%可信区间 1.27-4.22），p<0.01。
在这群年龄较大的有牙列的人群中，牙周炎与气流受限显著相关，独立于其他已知的危险因素。
