Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen, 361005, R. P. China.
Fujian Province Universities and Colleges Engineering Research Center for Marine Biomedical Resources Utilization, Xiamen Medical College, 1999 Guankouzhong Road, Xiamen, 361023, R. P. China.
Chem Biodivers. 2020 Jun;17(6):e2000158. doi: 10.1002/cbdv.202000158. Epub 2020 May 13.
A unique polyketide cladosporactone A along with eight known compounds were isolated from the deep-sea-derived Cladosporium cladosporioides. The structure of cladosporactone A was established by spectroscopic analyses, and the absolute configuration was clarified by the theoretical ECD calculation. Cladosporactone A is the first member of polyketide with the 7-methylisochromen-3-one skeleton.
从深海来源的枝孢属 Cladosporium cladosporioides 中分离得到一种独特的聚酮化合物 cladosporactone A 以及八种已知化合物。通过光谱分析确定了 cladosporactone A 的结构，并通过理论 ECD 计算确定了其绝对构型。Cladosporactone A 是具有 7-甲基异色满-3-酮骨架的聚酮类化合物中的第一个成员。
