Department of Sport Rehabilitation, Dong Ju College, Busan 49318, Korea.
Department of Family Medicine, College of Medicine, Dong-A University, Busan 49201, Korea.
Int J Environ Res Public Health. 2020 Apr 4;17(7):2475. doi: 10.3390/ijerph17072475.
The fruit of (SC) is a well-known traditional herb used for pharmacological purposes in Asian countries (e.g., Korea, China, and Japan). In animal studies, SC extract supplementation had beneficial effects on muscle strength and lactate level. However, the effect of SC extract supplementation on skeletal muscle strength and lactate at rest in humans remains unclear. The purpose of this study was to evaluate the effect of SC extract supplementation on quadriceps muscle strength (QMS) and lactate at rest in adult women. Forty five healthy post-menopausal middle-aged women (61.9 ± 8.4 years) were randomly divided into the SC ( = 24) or the placebo group ( = 21). The SC group consumed 1000 mg of SC extract per day, whereas the placebo group consumed 1000 mg of starch per day for 12 weeks. The difference in muscle mass, physical function, and biomarkers and the relative changes between baseline and 12 weeks were evaluated. We used two-factor repeated measures analysis of variance (ANOVA) to determine interaction (group × time) effects for variables. Statistical significance was accepted at < 0.05. In ANOVA results, QMS ( = 0.001) and lactate level ( = 0.038) showed significant interactions. With paired t-tests, QMS was significantly increased ( < 0.001) and lactate level at rest was significantly decreased ( < 0.05) after 12 weeks in the SC group. However, no interactions were found between the other variables. Supplementation of SC extract may help to improve QMS as well as decrease lactate level at rest in adult women. We believe that SC extract is a health supplement that can support healthy life in this population.
（SC）的果实是一种在亚洲国家（如韩国、中国和日本）用于药物目的的著名传统草药。在动物研究中，SC 提取物补充剂对肌肉力量和乳酸水平有有益的影响。然而，SC 提取物补充剂对人类静止时骨骼肌力量和乳酸的影响尚不清楚。本研究的目的是评估 SC 提取物补充剂对绝经后中年女性股四头肌力量（QMS）和静止时乳酸的影响。45 名健康绝经后中年女性（61.9 ± 8.4 岁）被随机分为 SC 组（n = 24）或安慰剂组（n = 21）。SC 组每天服用 1000 毫克 SC 提取物，而安慰剂组每天服用 1000 毫克淀粉，持续 12 周。评估肌肉质量、身体功能和生物标志物的差异以及基线和 12 周之间的相对变化。我们使用双因素重复测量方差分析（ANOVA）来确定变量的交互（组×时间）效应。统计显著性接受 < 0.05。在 ANOVA 结果中，QMS（ = 0.001）和乳酸水平（ = 0.038）显示出显著的交互作用。通过配对 t 检验，SC 组在 12 周后 QMS 显著增加（ < 0.001），静止时乳酸水平显著降低（ < 0.05）。然而，其他变量之间没有发现相互作用。SC 提取物的补充可能有助于提高成年女性的 QMS，并降低静止时的乳酸水平。我们相信 SC 提取物是一种健康补充剂，可以支持这一人群的健康生活。
