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用于乳腺异常分类的残差网络-自注意力深度特征聚合-50

ResNet-SCDA-50 for Breast Abnormality Classification.

作者信息

Yu Xiang, Kang Cheng, Guttery David S, Kadry Seifedine, Chen Yang, Zhang Yu-Dong

出版信息

IEEE/ACM Trans Comput Biol Bioinform. 2021 Jan-Feb;18(1):94-102. doi: 10.1109/TCBB.2020.2986544. Epub 2021 Feb 3.

Abstract

(Aim) Breast cancer is the most common cancer in women and the second most common cancer worldwide. With the rapid advancement of deep learning, the early stages of breast cancer development can be accurately detected by radiologists with the help of artificial intelligence systems. (Method) Based on mammographic imaging, a mainstream clinical breast screening technique, we present a diagnostic system for accurate classification of breast abnormalities based on ResNet-50. To improve the proposed model, we created a new data augmentation framework called SCDA (Scaling and Contrast limited adaptive histogram equalization Data Augmentation). In its procedure, we first conduct the scaling operation to the original training set, followed by applying contrast limited adaptive histogram equalisation (CLAHE) to the scaled training set. By stacking the training set after SCDA with the original training set, we formed a new training set. The network trained by the augmented training set, was coined as ResNet-SCDA-50. Our system, which aims at a binary classification on mammographic images acquired from INbreast and MINI-MIAS, classifies masses, microcalcification as "abnormal", while normal regions are classified as "normal". (Results) We present the first attempt to use the image contrast enhancement method as the data augmentation method, resulting in an averaged 98.55 percent specificity and 92.83 percent sensitivity, which gives our best model an overall accuracy of 95.74 percent. (Conclusion) Our proposed method is effective in classifying breast abnormality.

摘要

(目的)乳腺癌是女性中最常见的癌症,也是全球第二大常见癌症。随着深度学习的快速发展,放射科医生借助人工智能系统能够准确检测乳腺癌的早期发展阶段。(方法)基于乳腺钼靶成像(一种主流的临床乳腺筛查技术),我们提出了一种基于ResNet - 50的乳腺异常准确分类诊断系统。为改进所提出的模型,我们创建了一个名为SCDA(缩放和对比度受限自适应直方图均衡化数据增强)的新数据增强框架。在其过程中,我们首先对原始训练集进行缩放操作,然后对缩放后的训练集应用对比度受限自适应直方图均衡化(CLAHE)。通过将经过SCDA处理后的训练集与原始训练集堆叠,我们形成了一个新的训练集。由增强训练集训练的网络被命名为ResNet - SCDA - 50。我们的系统旨在对从INbreast和MINI - MIAS获取的乳腺钼靶图像进行二分类,将肿块、微钙化分类为“异常”,而正常区域分类为“正常”。(结果)我们首次尝试将图像对比度增强方法用作数据增强方法,得到的特异性平均为98.55%,灵敏度为92.83%,这使得我们的最佳模型总体准确率达到95.74%。(结论)我们提出的方法在乳腺异常分类方面是有效的。

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