Desselberger Ulrich, Gray Jim
is a Director of Research, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. Competing interests: none declared.
is a Head of the Enteric Virus Unit, Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK. Competing interests: none declared.
Medicine (Abingdon). 2009 Nov;37(11):594-598. doi: 10.1016/j.mpmed.2009.08.005. Epub 2009 Oct 31.
The virology, immunology, diagnosis, clinical symptoms, treatment, epidemiology and prevention measures relating to the most common viral causes of acute gastroenteritis (rotaviruses, human caliciviruses, astroviruses and enteric adenoviruses) are briefly reviewed. Uncommon viral causes of acute gastroenteritis and viruses causing gastroenteritis in immunodeficient patients are mentioned. The main change over the past three years has been the development, licensing and wide application of new live attenuated rotavirus vaccines.
本文简要回顾了与急性胃肠炎最常见病毒病因（轮状病毒、人杯状病毒、星状病毒和肠道腺病毒）相关的病毒学、免疫学、诊断、临床症状、治疗、流行病学及预防措施。文中还提及了急性胃肠炎不常见的病毒病因以及免疫功能低下患者发生胃肠炎的病毒病因。过去三年的主要变化是新型减毒活轮状病毒疫苗的研发、获批及广泛应用。
