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基孔肯雅热——一种新的全球威胁。

Chikungunya fever - A new global threat.

作者信息

Montero Antonio

机构信息

Miembro de la Carrera del Investigador Científico, Consejo de Investigaciones de la Universidad Nacional de Rosario (CIUNR), Rosario, Santa Fe, Argentina.

Centro de Medicina Tropical y Enfermedades Infecciosas Emergentes, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Rosario, Santa Fe, Argentina.

出版信息

Med Clin (Engl Ed). 2015 Aug 7;145(3):118-123. doi: 10.1016/j.medcle.2014.05.013. Epub 2016 Feb 1.

Abstract

The recent onset of epidemics caused by viruses such as Ebola, Marburg, Nipah, Lassa, coronavirus, West-Nile encephalitis, Saint Louis encephalitis, human immunodeficiency virus, dengue, yellow fever and Venezuelan haemorrhagic fever alerts about the risk these agents represent for the global health. Chikungunya virus represents a new threat. Surged from remote African regions, this virus has become endemic in the Indic ocean basin, the Indian subcontinent and the southeast of Asia, causing serious epidemics in Africa, Indic Ocean Islands, Asia and Europe. Due to their epidemiological and biological features and the global presence of their vectors, chikungunya represents a serious menace and could become endemic in the Americas. Although chikungunya infection has a low mortality rate, its high attack ratio may collapse the health system during epidemics affecting a sensitive population. In this paper, we review the clinical and epidemiological features of chikungunya fever as well as the risk of its introduction into the Americas. We remark the importance of the epidemiological control and mosquitoes fighting in order to prevent this disease from being introduced into the Americas.

摘要

近期由埃博拉病毒、马尔堡病毒、尼帕病毒、拉沙病毒、冠状病毒、西尼罗河脑炎病毒、圣路易斯脑炎病毒、人类免疫缺陷病毒、登革热病毒、黄热病病毒和委内瑞拉出血热病毒等引发的疫情,警示了这些病原体对全球健康构成的风险。基孔肯雅病毒是一种新的威胁。该病毒起源于非洲偏远地区,现已在印度洋盆地、印度次大陆和亚洲东南部地区流行,在非洲、印度洋岛屿、亚洲和欧洲引发了严重疫情。鉴于其流行病学和生物学特征以及其传播媒介在全球的分布,基孔肯雅病毒构成了严重威胁,有可能在美洲地区流行。尽管基孔肯雅病毒感染死亡率较低,但在影响易感人群的疫情期间,其高感染率可能导致卫生系统不堪重负。本文回顾了基孔肯雅热的临床和流行病学特征以及该病毒传入美洲的风险。我们强调了开展流行病学监测和蚊虫防治工作对于预防该疾病传入美洲的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc7/7140256/7e01cb60e16d/gr1.jpg

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