Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.
KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.
Mar Drugs. 2020 Apr 10;18(4):203. doi: 10.3390/md18040203.
Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activities. Here we classify these peptides on the basis of their chemical structure and discuss a number of representatives of each class that reflect the extraordinary potential of this family as a source of new drugs.
含恶唑环的肽大多来源于海洋,它们形成了一个引人入胜的家族,具有广泛的生物活性。在这里,我们根据它们的化学结构对这些肽进行分类,并讨论了每一类的一些代表性肽,这些代表性肽反映了这个家族作为新药来源的非凡潜力。