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Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26381. Epub 2016 Dec 1.
2
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Saudi Med J. 2015 Jun;36(6):704-12. doi: 10.15537/smj.2015.6.11247.
3
Association between maternal and fetal factors and quality of cord blood as a source of stem cells.母体和胎儿因素与作为干细胞来源的脐带血质量之间的关联。
Rev Bras Hematol Hemoter. 2015 Jan-Feb;37(1):38-42. doi: 10.1016/j.bjhh.2014.07.023. Epub 2014 Nov 26.
4
Optimal method for collection of umbilical cord blood: an Egyptian trial for a public cord blood bank.脐带血采集的最佳方法：埃及一家公共脐带血库的试验
Transfusion. 2015 Jun;55(6):1263-8. doi: 10.1111/trf.12978. Epub 2015 Jan 7.
5
Feasibility of collecting umbilical cord blood in jordan and the effect of maternal and neonatal factors on hematopoietic stem cell content.在约旦采集脐带血的可行性及其对母婴因素对造血干细胞含量的影响。
Mediterr J Hematol Infect Dis. 2014 Feb 18;6(1):e2014019. doi: 10.4084/MJHID.2014.019. eCollection 2014.
6
Umbilical cord mesenchymal stem cells: the new gold standard for mesenchymal stem cell-based therapies?脐带间充质干细胞：基于间充质干细胞疗法的新金标准？
Tissue Eng Part B Rev. 2014 Oct;20(5):523-44. doi: 10.1089/ten.TEB.2013.0664. Epub 2014 Apr 22.
7
Optimizing donor selection for public cord blood banking: influence of maternal, infant, and collection characteristics on cord blood unit quality.优化公共脐带血库的供者选择：产妇、婴儿和采集特征对脐带血细胞质量的影响。
Transfusion. 2014 Feb;54(2):340-52. doi: 10.1111/trf.12257. Epub 2013 May 27.
8
Factors predicting the hematopoietic stem cells content of the umbilical cord blood.预测脐带血造血干细胞含量的因素。
Transfus Apher Sci. 2013 Apr;48(2):247-52. doi: 10.1016/j.transci.2013.01.003. Epub 2013 Feb 14.
9
Does umbilical cord blood-derived CD34+ cell concentration depend on the weight and sex of a full-term infant?脐血来源的CD34+细胞浓度是否取决于足月婴儿的体重和性别？
J Pediatr Hematol Oncol. 2012 Apr;34(3):184-7. doi: 10.1097/MPH.0b013e318249adb6.
10
Impact of maternal and neonatal factors on CD34+ cell count, total nucleated cells, and volume of cord blood.孕产妇和新生儿因素对脐带血CD34+细胞计数、总核细胞数及体积的影响。
Pediatr Transplant. 2008 Dec;12(8):868-73. doi: 10.1111/j.1399-3046.2008.00932.x. Epub 2008 Jul 17.

孕产妇和新生儿因素对脐带血CD34细胞的影响。

Impact of maternal and neonatal factors on umbilical cord CD34 cells.

作者信息

Rowisha Mohamed A, El-Shanshory Mohamed R, El-Hawary Eslam E, Ahmed Amira Youssef, Altoraky Shafeq Ryad Mustafa

机构信息

Pediatric Department, Faculty of Medicine, Tanta University Faculty of Medicine, Tanta University, Tanta, Egypt.

Clinical Pathology Department, Faculty of Medicine, Tanta University Faculty of Medicine, Tanta University, Tanta, Egypt.

出版信息

Stem Cell Investig. 2020 Mar 31;7:5. doi: 10.21037/sci.2020.03.01. eCollection 2020.

DOI:10.21037/sci.2020.03.01
PMID:32309419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7154318/
Abstract

BACKGROUND

The achievement of optimal number of CD34 umbilical cord stem cells is essential for successful umbilical cord stem cell transplantation. So the aim of this study was to assess the potential effect of both maternal and neonatal factors on the umbilical cord blood CD34 cell count.

METHODS

The study was done on umbilical cord blood samples obtained from 20 mothers during labor. Their ages ranged from 22 to 34 years and were subjected to history taking, physical examination of the baby and assessment of the CD34 cells count in umbilical cord blood.

RESULTS

Number of previous live births and weight of the baby had a significant effect on CD34 cells count while the sex of the baby, delivery route, maternal age and gestation period had no significant effect on CD34 cells count.

CONCLUSIONS

Umbilical cord blood-derived CD34 cell count is better with good weight and first babies and decreased with subsequent babies.

摘要

背景

获得最佳数量的CD34脐带干细胞对于成功进行脐带干细胞移植至关重要。因此，本研究的目的是评估母亲和新生儿因素对脐带血CD34细胞计数的潜在影响。

方法

本研究对20名母亲分娩时采集的脐带血样本进行。她们的年龄在22至34岁之间，对其进行病史采集、婴儿体格检查以及脐带血中CD34细胞计数评估。

结果

既往活产次数和婴儿体重对CD34细胞计数有显著影响，而婴儿性别、分娩方式、母亲年龄和妊娠期对CD34细胞计数无显著影响。

结论

体重良好的初产婴儿的脐带血来源的CD34细胞计数较高，而经产婴儿的计数则降低。