接受使用干血斑进行家庭茶碱监测。
Acceptance of domiciliary theophylline monitoring using dried blood spots.
作者信息
Rattenbury J M, Tsanakas J
机构信息
Department of Chemical Pathology, Children's Hospital, Sheffield.
出版信息
Arch Dis Child. 1988 Dec;63(12):1449-52. doi: 10.1136/adc.63.12.1449.
Filter paper cards incorporating dried blood spots for the measurement of theophylline concentrations were returned by 62 out of 100 asthmatic children sent kits with instructions for their collection. Analysis of the blood spots showed that 37 (61%) of the children who returned them had less than therapeutic blood theophylline concentrations, in 21 (34%) they were therapeutic, and in three (5%) they were potentially toxic. The results indicate that most asthmatic children would comply with requests for home monitoring of theophylline concentrations, and that only one third of children receiving theophylline achieved blood concentrations and that only one third of children receiving theophylline achieved blood concentrations within the therapeutic range.
100名哮喘儿童收到了附有采血说明的试剂盒，其中62名儿童返还了用于测定茶碱浓度的干血斑滤纸片。对血斑的分析表明，返还血斑的儿童中，37名（61%）的茶碱血药浓度低于治疗浓度，21名（34%）处于治疗浓度，3名（5%）可能中毒。结果表明，大多数哮喘儿童会遵守在家监测茶碱浓度的要求，并且接受茶碱治疗的儿童中只有三分之一的血药浓度达到治疗范围。
Zotero 插件