Chandran Hema, Meena Mukesh, Barupal Tansukh, Sharma Kanika
Department of Botany, Mohanlal Sukhadia University, Udaipur, 313001, Rajasthan, India.
Biotechnol Rep (Amst). 2020 Apr 20;26:e00450. doi: 10.1016/j.btre.2020.e00450. eCollection 2020 Jun.
Plants have been used throughout the world for its medicinal powers since ancient time. The pharmacological properties of plants are based on their phytochemical components especially the secondary metabolites which are outstanding sources of value added bioactive compounds. Secondary metabolites have complex chemical composition and are produced in response to various forms of stress to perform different physiological tasks in plants. They are used in pharmaceutical industries, cosmetics, dietary supplements, fragrances, flavors, dyes, etc. Extended use of these metabolites in various industrial sectors has initiated a need to focus research on increasing the production by employing plant tissue culture (PTC) techniques and optimizing their large scale production using bioreactors. PTC techniques being independent of climatic and geographical conditions will provide an incessant, sustainable, economical and viable production of secondary metabolites. This review article intends to assess the advantages of using plant tissue culture, distribution of important secondary metabolites in plant families, strategies involved for optimal metabolite production and the industrial importance of selected secondary metabolites.
自古以来，植物就在世界各地因其药用功效而被使用。植物的药理特性基于其植物化学成分，特别是次生代谢产物，它们是有附加值的生物活性化合物的重要来源。次生代谢产物具有复杂的化学成分，是植物为应对各种形式的胁迫而产生的，以执行不同的生理任务。它们被用于制药行业、化妆品、膳食补充剂、香料、调味剂、染料等。这些代谢产物在各个工业领域的广泛应用引发了人们对通过采用植物组织培养（PTC）技术来提高产量以及利用生物反应器优化其大规模生产进行研究的需求。植物组织培养技术不受气候和地理条件的限制，将为次生代谢产物提供持续、可持续、经济且可行的生产方式。这篇综述文章旨在评估使用植物组织培养的优势、重要次生代谢产物在植物科中的分布、优化代谢产物生产所涉及的策略以及所选次生代谢产物的工业重要性。
