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重庆市主城区 136 例 COVID-19 的流行病学和临床特征。

Epidemiological and clinical characteristics of 136 cases of COVID-19 in main district of Chongqing.

机构信息

Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, 400014, China.

Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, 400014, China.

出版信息

J Formos Med Assoc. 2020 Jul;119(7):1180-1184. doi: 10.1016/j.jfma.2020.04.019. Epub 2020 Apr 29.

Abstract

BACKGROUND

We did a comprehensive exploration of the epidemiological and clinical characteristics of 136 patients with confirmed COVID-19 in main district of Chongqing which was adjacent to the west of Hubei province.

METHODS

This study was conducted on 136 patients with COVID-19 in main district of Chongqing from Jan 25 to Feb 20, 2020. Data of patients included demographic, epidemiological, clinical features, chest radiographs of imported cases, local cases, second-generation cases and third-generation cases. Student's t-test was adopted for quantitative variables while Pearson Chi-squared test or Fisher's exact test for categorical variables.

RESULTS

The median age was 47 years and common symptoms of illness were cough (50.7%), fever (47.1%) and fatigue (14.0%). The time from contact symptomatic case to illness was 7.7 days, and 88 patients (64.7%) were cluster cases, radiological evidence found bilateral lung involvement was common (57.4%).Compared with the imported cases, the local cases were significantly older, the proportion of men is lower. There was higher proportion of cluster cases in local cases. Unlike imported cases, which fever was the dominant symptom, the local cases have more cough patients, with a significant higher proportion of asymptomatic patients. The third-generation cases have a significant higher proportion of asymptomatic patients.

CONCLUSION

We concluded the epidemiological and clinical characteristics of the cases andsuggested to take more comprehensive measures for screening patients, especially for elderly person, avoid family gatherings, and implement more closely surveillance of suspect patients and their close contacts.

摘要

背景

我们对毗邻湖北省西部的重庆市主城区 136 例确诊 COVID-19 患者的流行病学和临床特征进行了全面探讨。

方法

本研究于 2020 年 1 月 25 日至 2 月 20 日对重庆市主城区的 136 例 COVID-19 患者进行了研究。患者数据包括人口统计学、流行病学、临床特征、输入性病例、本地病例、第二代病例和第三代病例的胸部 X 光片。定量变量采用 Student's t 检验,分类变量采用 Pearson Chi-squared 检验或 Fisher's exact 检验。

结果

中位年龄为 47 岁,常见症状为咳嗽(50.7%)、发热(47.1%)和乏力(14.0%)。从接触有症状病例到发病的时间为 7.7 天,88 例(64.7%)为聚集性病例,影像学证据显示双肺受累常见(57.4%)。与输入性病例相比,本地病例年龄较大,男性比例较低。本地病例聚集性病例比例较高。与输入性病例发热为主的症状不同,本地病例咳嗽患者较多,无症状患者比例明显较高。第三代病例无症状患者比例明显较高。

结论

我们总结了病例的流行病学和临床特征,并建议采取更全面的措施筛查患者,特别是对老年人,避免家庭聚会,并对疑似患者及其密切接触者实施更密切的监测。

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