Department of Pharmacy, University of Salerno, Fisciano, SA, Italy.
ImmunePharma srl, Fisciano, SA, Italy.
Nat Prod Res. 2021 Dec;35(23):5360-5363. doi: 10.1080/14786419.2020.1761359. Epub 2020 May 14.
Many herbal agents and medicinal plants have provided clinical interest due to their therapeutic properties, availability and lower side effects. The aim of this study was to understand the anti-bacterial activity of the combination of (PEL), (ADH) and N-Acetyl-L-Cysteine (NAC) (NAXX). We found that NAXX had strong and long-term bacteriostatic activity, which was related to its anti-oxidant activity. Our data demonstrate that NAXX is an innovative medicinal plant-derived strategy to manage of oxidative stress- and microbial-based diseases.
许多草药制剂和药用植物因其治疗特性、可用性和较低的副作用而引起了临床关注。本研究的目的是了解(PEL)、(ADH)和 N-乙酰-L-半胱氨酸(NAC)(NAXX)组合的抗细菌活性。我们发现 NAXX 具有强大而持久的抑菌活性,这与其抗氧化活性有关。我们的数据表明,NAXX 是一种创新的药用植物衍生策略,可用于治疗氧化应激和微生物相关疾病。