Nita Loredana Elena, Ghilan Alina, Rusu Alina Gabriela, Neamtu Iordana, Chiriac Aurica P
"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41-A, RO-700487 Iasi, Romania.
Pharmaceutics. 2020 May 13;12(5):449. doi: 10.3390/pharmaceutics12050449.
(1) Background: The fascinating properties of currently synthesized aerogels associated with the flexible approach of sol-gel chemistry play an important role in the emergence of special biomedical applications. Although it is increasingly known and mentioned, the potential of aerogels in the medical field is not sufficiently explored. Interest in aerogels has increased greatly in recent decades due to their special properties, such as high surface area, excellent thermal and acoustic properties, low density and thermal conductivity, high porosity, flame resistance and humidity, and low refractive index and dielectric constant. On the other hand, high manufacturing costs and poor mechanical strength limit the growth of the market. (2) Results: In this paper, we analyze more than 180 articles from recent literature studies focused on the dynamics of aerogels research to summarize the technologies used in manufacturing and the properties of materials based on natural polymers from renewable sources. Biomedical applications of these bio-based materials are also introduced. (3) Conclusions Due to their complementary functionalities (bioactivity, biocompatibility, biodegradability, and unique chemistry), bio-based materials provide a vast capability for utilization in the field of interdisciplinary and multidisciplinary scientific research.
(1) 背景：当前合成气凝胶的迷人特性与溶胶 - 凝胶化学的灵活方法相关，在特殊生物医学应用的出现中发挥着重要作用。尽管气凝胶越来越为人所知并被提及，但其在医学领域的潜力尚未得到充分探索。近几十年来，由于气凝胶具有高比表面积、优异的热学和声学性能、低密度和低导热性、高孔隙率、阻燃性和防潮性以及低折射率和介电常数等特殊性能，人们对它的兴趣大增。另一方面，高制造成本和较差的机械强度限制了市场的增长。(2) 结果：在本文中，我们分析了最近文献研究中180多篇聚焦气凝胶研究动态的文章，以总结制造中使用的技术以及基于可再生资源的天然聚合物材料的性能。还介绍了这些生物基材料的生物医学应用。(3) 结论：由于其互补功能（生物活性、生物相容性、生物可降解性和独特化学性质），生物基材料在跨学科和多学科科学研究领域具有巨大的应用潜力。
