Suppr超能文献

中国西北地区 46609 人中的日间温差对血压的影响。

The effect of diurnal temperature range on blood pressure among 46,609 people in Northwestern China.

机构信息

Institute of Epidemiology and Statistics, School of Public Health, Lanzhou University, Lanzhou 73000, China.

Institute of Epidemiology and Statistics, School of Public Health, Lanzhou University, Lanzhou 73000, China.

出版信息

Sci Total Environ. 2020 Aug 15;730:138987. doi: 10.1016/j.scitotenv.2020.138987. Epub 2020 Apr 26.

Abstract

BACKGROUND

A large number of studies have found a positive association between diurnal temperature range (DTR) and cardiovascular diseases (CVDs) incidence and mortality. Few studies regarding the effects of DTR on blood pressure (BP) are available.

OBJECTIVE

To investigate the effects of DTR on BP in Jinchang, northwestern China.

METHODS

Based on a prospective cohort research, a total of 46,609 baseline survey data were collected from 2011 to 2015. The meteorological observation data and environmental monitoring data were collected in the same period. The generalized additive model (GAM) was used to estimate the relationship between DTR and BP after adjusting for confounding variables.

RESULTS

Our study found that there was a positive linear correlation between DTR and systolic blood pressure (SBP) and plus pressure (PP), and a negative linear correlation between DTR and diastolic blood pressure (DBP). With a 1 °C increase of DTR, SBP and PP increased 0.058 mmHg (95%CI: 0.018-0.097) and 0.114 mmHg (95%CI: 0.059-0.168) respectively, and DBP decreased 0.039 mmHg (95%CI:-0.065 ~ -0.014). There was a significant interaction between season and DTR on SBP and PP. DTR had the greatest impact on SBP and PP in hot season. The association between DTR and BP varied significantly by education level.

CONCLUSION

There was a significant association between DTR and BP in Jinchang, an area with large temperature change at high altitudes in northwestern China. These results provide new evidence that DTR is an independent risk factor for BP changes among general population. Therefore, effective control and management of BP in the face of temperature changes can help prevent CVDs.

摘要

背景

大量研究发现日较差(DTR)与心血管疾病(CVDs)发病率和死亡率之间存在正相关关系。关于 DTR 对血压(BP)的影响的研究较少。

目的

探讨中国西北部金昌市 DTR 对 BP 的影响。

方法

基于前瞻性队列研究,于 2011 年至 2015 年共收集了 46609 例基线调查数据。同期收集气象观测数据和环境监测数据。采用广义相加模型(GAM)调整混杂因素后,估计 DTR 与 BP 之间的关系。

结果

本研究发现 DTR 与收缩压(SBP)和脉压(PP)呈正线性相关,与舒张压(DBP)呈负线性相关。DTR 每升高 1°C,SBP 和 PP 分别增加 0.058mmHg(95%CI:0.018-0.097)和 0.114mmHg(95%CI:0.059-0.168),DBP 降低 0.039mmHg(95%CI:-0.065~-0.014)。SBP 和 PP 季节与 DTR 之间存在显著交互作用。DTR 对高温季节的 SBP 和 PP 影响最大。DTR 与 BP 的相关性在教育水平上差异有统计学意义。

结论

在中国西北部高海拔地区气温变化较大的金昌,DTR 与 BP 之间存在显著关联。这些结果提供了新的证据,表明 DTR 是一般人群 BP 变化的独立危险因素。因此,面对温度变化时有效控制和管理 BP 有助于预防 CVDs。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验