COVID-19 感染患者和疑似肺栓塞患者中的 D-二聚体。
D-dimer in patients infected with COVID-19 and suspected pulmonary embolism.
机构信息
Servei de Pneumologia. Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain; CibeRes, Ciber de Enfermedades Respiratorias, Bunyola, Spain; Germans Trias i Pujol Research Institute (IGTP), Badalona, Barcelona, Spain.
Servei de Pneumologia. Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain; Departament de Medicina. Universitat Autònoma de Barcelona, Barcelona, Spain.
出版信息
Respir Med. 2020 Aug;169:106023. doi: 10.1016/j.rmed.2020.106023. Epub 2020 May 13.
OBJECTIVE
To analyze the risk factors for pulmonary embolism (PE) in patients infected with COVID-19.
METHODS
We conducted an observational, retrospective study. Patients with severe infection with COVID-19 and suspected PE were included.
RESULTS
Patients with higher levels of D-dimer and those requiring intubation were at a higher risk of developing PE. Higher D-dimer levels were associated with a greater probability of PE 3, 6, 9 and 12 days after determining D-dimer levels with an OR of 1.7, 2.0, 2.4 and 2.4, respectively.
CONCLUSION
In conclusion, patients infected with COVID-19 requiring OTI with higher levels of D-dimer have an increased risk of developing PE.
目的
分析 COVID-19 感染患者发生肺栓塞（PE）的危险因素。
方法
我们进行了一项观察性、回顾性研究。纳入了患有严重 COVID-19 感染和疑似 PE 的患者。
结果
D-二聚体水平较高且需要插管的患者发生 PE 的风险更高。较高的 D-二聚体水平与确定 D-二聚体水平后 3、6、9 和 12 天发生 PE 的可能性更大相关，OR 值分别为 1.7、2.0、2.4 和 2.4。
结论
总之，需要 OTI 且 D-二聚体水平较高的 COVID-19 感染患者发生 PE 的风险增加。
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