Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Clinical Research Center, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
BMC Cancer. 2020 May 26;20(1):473. doi: 10.1186/s12885-020-06977-0.
Self-sampling for HPV testing, as an alternative to the conventional speculum based sampling, is highly acceptable to women of screening ages. The aim of this study was to describe older women's (60 to 75 years) experiences of self-sampling.
In Sweden a descriptive study with quantitative and qualitative methods was designed to collect data from a survey of women who participated in self-sampling for HPV testing. Individual interviews were done with women who tested positive in the first self-sampling, and were either negative in their second HPV test or were positive in their second HPV test, but without precancerous lesions or cancer.
Of 893 eligible women, 868 (97.2%) answered the survey. Among the surveyed women, 49.2% reported it was very easy to perform self-sampling, 46.8% answered it was easy and 2.0% answered it was not easy. A majority (58.9%) answered that they prefer self-sampling, 16.5% that they prefer sample collection by a healthcare provider, 23.7% did not have any preference and 0.9% did not answer the question. In the interviews, 13 of 16 invited women participated. Most of them reported that they prefer self-sampling because it was easy to perform, less embarrassing and less time consuming than a visit to a clinic. The majority of women reported that they were not worried when informed about having an HPV positive test. Overall, participating women with better knowledge about the significance of an HPV infection were more worried about having a positive HPV test.
Cervical cancer remains a highly preventable disease through screening and early treatment. Our results indicated that vaginal self-sampling for HPV testing was a well-accepted method for cervical cancer prevention in this group of older women.
https://www.researchweb.org/is/en/fouckfuu/project/272587. Registered 24 June 2019-retrospectively registered. www.researchweb.org.
HPV 检测的自我采样作为传统阴道镜采样的替代方法，受到筛查年龄段女性的高度认可。本研究旨在描述老年女性（60-75 岁）对自我采样的体验。
在瑞典，采用描述性研究，结合定量和定性方法，对参与 HPV 自我采样检测的女性进行了一项调查，收集数据。对第一次自我采样检测呈阳性、第二次 HPV 检测结果为阴性或第二次 HPV 检测结果为阳性但无癌前病变或癌症的女性进行了个体访谈。
在 893 名符合条件的女性中，868 名（97.2%）回答了调查问题。在接受调查的女性中，49.2%报告说自我采样非常容易，46.8%报告说容易，2.0%报告说不容易。大多数女性（58.9%）回答更喜欢自我采样，16.5%回答更喜欢由医疗保健提供者进行样本采集，23.7%没有任何偏好，0.9%未回答该问题。在访谈中，邀请了 16 名女性中的 13 名参加。她们大多表示，更喜欢自我采样，因为自我采样易于操作，比去诊所就诊尴尬程度更低、用时更短。大多数女性报告说，当被告知 HPV 检测呈阳性时，她们并不担心。总体而言，对 HPV 感染意义有较好了解的参与女性对 HPV 检测呈阳性的担忧程度更高。
通过筛查和早期治疗，宫颈癌仍然是一种高度可预防的疾病。我们的研究结果表明，对于这组老年女性，HPV 检测的阴道自我采样是一种可接受的宫颈癌预防方法。
https://www.researchweb.org/is/en/fouckfuu/project/272587。于 2019 年 6 月 24 日注册-回顾性注册。www.researchweb.org。
