Habtemariam Solomon
Pharmacognosy Research Laboratories & Herbal Analysis Services UK, University of Greenwich, Chatham-Maritime, Kent ME4 4TB, UK.
Biomedicines. 2020 May 25;8(5):135. doi: 10.3390/biomedicines8050135.
(L.) Quél. is a higher fungi or mushroom which is now known by its accepted scientific name as (L.) Lloyd (family Polyporaceae). The polysaccharides, primarily two commercial products from China and Japan as PSP and PSK, respectively, have been claimed to serve as adjuvant therapy for cancer. In this paper, research advances in this field, including direct cytotoxicity in cancer cells and immunostimulatory effects, are scrutinised at three levels: in vitro, in vivo and clinical outcomes. The level of activity in the various cancers, key targets (both in cancer and immune cells) and pharmacological efficacies are discussed.
（L.）Quél.是一种高等真菌或蘑菇，现在它的公认学名是（L.）劳埃德（多孔菌科）。多糖，主要是分别来自中国和日本的两种商业产品PSP和PSK，据称可作为癌症的辅助治疗。本文从体外、体内和临床结果三个层面审视了该领域的研究进展，包括对癌细胞的直接细胞毒性和免疫刺激作用。讨论了在各种癌症中的活性水平、关键靶点（癌细胞和免疫细胞中的靶点）以及药理疗效。
